MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT

A review of the literature regarding magnesium (Mg²⁺) imbalance in children and adolescents in intensive care unit settings was conducted. The search for relevant information was performed using the Cochrane Library, PubMed, ScienceDirect, and Medscape databases, with keywords such as "magnesiu...

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Main Authors: YU.V. BYKOV, A. N. OBEDIN, V.V. FISCHER, E.V. VOLKOV, O.V. ZINCHENKO, A.A. MURAVYOVA, I.V. YATSUK
Format: Article
Language:English
Published: Avicenna Tajik State Medical University 2025-07-01
Series:Паёми Сино
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Online Access:https://doi.org/10.25005/2074-0581-2025-27-2-406-415
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author YU.V. BYKOV
A. N. OBEDIN
V.V. FISCHER
E.V. VOLKOV
O.V. ZINCHENKO
A.A. MURAVYOVA
I.V. YATSUK
author_facet YU.V. BYKOV
A. N. OBEDIN
V.V. FISCHER
E.V. VOLKOV
O.V. ZINCHENKO
A.A. MURAVYOVA
I.V. YATSUK
author_sort YU.V. BYKOV
collection DOAJ
description A review of the literature regarding magnesium (Mg²⁺) imbalance in children and adolescents in intensive care unit settings was conducted. The search for relevant information was performed using the Cochrane Library, PubMed, ScienceDirect, and Medscape databases, with keywords such as "magnesium", "hypomagnesemia", "hypermagnesemia", "children", "adolescents", and "intensive care". The review included sources published over the past 10 years (2014-2024). The inclusion criteria for the review required works to describe the pathogenesis, clinical manifestations, and correction methods for Mg²⁺ imbalance in pediatric intensive care practice. Articles focusing on the clinical picture and management of hypo- and hypermagnesemia in adult patients were excluded. Despite the high prevalence of Mg²⁺ imbalance among children and adolescents, this electrolyte disorder often goes unnoticed, particularly in intensive care patients. Hypomagnesemia is more common and can arise from acquired or genetic causes. Its clinical symptoms are highly nonspecific and can affect various organs and systems; these symptoms frequently occur in conjunction with hypokalemia and hypocalcemia. To correct acute and severe hypomagnesemia in children, intravenous administration of magnesium sulfate is recommended at a dose of 25-50 mg/kg. Hypermagnesemia is relatively rare, typically occurring in conjunction with renal failure and presenting with nonspecific symptoms. Treatment for high levels of Mg²⁺ involves the intravenous administration of calcium gluconate or calcium chloride, along with intravenous therapy. Timely diagnosis and treatment of Mg²⁺ imbalance in pediatric intensive care are crucial for providing adequate care to severely ill children.
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spelling doaj-art-f18ac39d2f0a4ae7a8d7c568cf4c2d0a2025-07-04T06:53:53ZengAvicenna Tajik State Medical UniversityПаёми Сино2074-05812959-63272025-07-0127240641510.25005/2074-0581-2025-27-2-406-415MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNITYU.V. BYKOV0A. N. OBEDIN1V.V. FISCHER2E.V. VOLKOV3O.V. ZINCHENKO4A.A. MURAVYOVA5I.V. YATSUK6Department of Anesthesiology and Resuscitation with a Course of DPO, Stavropol State Medical University, Stavropol, Russian FederationStavropol Regional Clinical Perinatal Center No. 1, Stavropol, Russian FederationShpakovskaya District Hospital, Mikhaylovsk, Russian FederationCity Clinical Hospital of Emergency Medical Care, Stavropol, Russian FederationDepartment of Anesthesiology and Resuscitation with a Course of DPO, Stavropol State Medical University, Stavropol, Russian FederationDepartment of Anesthesiology and Resuscitation with a Course of DPO, Stavropol State Medical University, Stavropol, Russian FederationStavropol City Clinical Emergency Hospital, Stavropol, Russian FederationA review of the literature regarding magnesium (Mg²⁺) imbalance in children and adolescents in intensive care unit settings was conducted. The search for relevant information was performed using the Cochrane Library, PubMed, ScienceDirect, and Medscape databases, with keywords such as "magnesium", "hypomagnesemia", "hypermagnesemia", "children", "adolescents", and "intensive care". The review included sources published over the past 10 years (2014-2024). The inclusion criteria for the review required works to describe the pathogenesis, clinical manifestations, and correction methods for Mg²⁺ imbalance in pediatric intensive care practice. Articles focusing on the clinical picture and management of hypo- and hypermagnesemia in adult patients were excluded. Despite the high prevalence of Mg²⁺ imbalance among children and adolescents, this electrolyte disorder often goes unnoticed, particularly in intensive care patients. Hypomagnesemia is more common and can arise from acquired or genetic causes. Its clinical symptoms are highly nonspecific and can affect various organs and systems; these symptoms frequently occur in conjunction with hypokalemia and hypocalcemia. To correct acute and severe hypomagnesemia in children, intravenous administration of magnesium sulfate is recommended at a dose of 25-50 mg/kg. Hypermagnesemia is relatively rare, typically occurring in conjunction with renal failure and presenting with nonspecific symptoms. Treatment for high levels of Mg²⁺ involves the intravenous administration of calcium gluconate or calcium chloride, along with intravenous therapy. Timely diagnosis and treatment of Mg²⁺ imbalance in pediatric intensive care are crucial for providing adequate care to severely ill children.https://doi.org/10.25005/2074-0581-2025-27-2-406-415magnesiumhypomagnesemiahypermagnesemiachildren and adolescentsintensive care.
spellingShingle YU.V. BYKOV
A. N. OBEDIN
V.V. FISCHER
E.V. VOLKOV
O.V. ZINCHENKO
A.A. MURAVYOVA
I.V. YATSUK
MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
Паёми Сино
magnesium
hypomagnesemia
hypermagnesemia
children and adolescents
intensive care.
title MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
title_full MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
title_fullStr MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
title_full_unstemmed MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
title_short MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT
title_sort management of magnesium imbalance in the pediatric intensive care unit
topic magnesium
hypomagnesemia
hypermagnesemia
children and adolescents
intensive care.
url https://doi.org/10.25005/2074-0581-2025-27-2-406-415
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