MANAGEMENT OF MAGNESIUM IMBALANCE IN THE PEDIATRIC INTENSIVE CARE UNIT

A review of the literature regarding magnesium (Mg²⁺) imbalance in children and adolescents in intensive care unit settings was conducted. The search for relevant information was performed using the Cochrane Library, PubMed, ScienceDirect, and Medscape databases, with keywords such as "magnesiu...

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Main Authors: YU.V. BYKOV, A. N. OBEDIN, V.V. FISCHER, E.V. VOLKOV, O.V. ZINCHENKO, A.A. MURAVYOVA, I.V. YATSUK
Format: Article
Language:English
Published: Avicenna Tajik State Medical University 2025-07-01
Series:Паёми Сино
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Online Access:https://doi.org/10.25005/2074-0581-2025-27-2-406-415
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Summary:A review of the literature regarding magnesium (Mg²⁺) imbalance in children and adolescents in intensive care unit settings was conducted. The search for relevant information was performed using the Cochrane Library, PubMed, ScienceDirect, and Medscape databases, with keywords such as "magnesium", "hypomagnesemia", "hypermagnesemia", "children", "adolescents", and "intensive care". The review included sources published over the past 10 years (2014-2024). The inclusion criteria for the review required works to describe the pathogenesis, clinical manifestations, and correction methods for Mg²⁺ imbalance in pediatric intensive care practice. Articles focusing on the clinical picture and management of hypo- and hypermagnesemia in adult patients were excluded. Despite the high prevalence of Mg²⁺ imbalance among children and adolescents, this electrolyte disorder often goes unnoticed, particularly in intensive care patients. Hypomagnesemia is more common and can arise from acquired or genetic causes. Its clinical symptoms are highly nonspecific and can affect various organs and systems; these symptoms frequently occur in conjunction with hypokalemia and hypocalcemia. To correct acute and severe hypomagnesemia in children, intravenous administration of magnesium sulfate is recommended at a dose of 25-50 mg/kg. Hypermagnesemia is relatively rare, typically occurring in conjunction with renal failure and presenting with nonspecific symptoms. Treatment for high levels of Mg²⁺ involves the intravenous administration of calcium gluconate or calcium chloride, along with intravenous therapy. Timely diagnosis and treatment of Mg²⁺ imbalance in pediatric intensive care are crucial for providing adequate care to severely ill children.
ISSN:2074-0581
2959-6327