The Impact of Overexpression of the Mouse Ortholog of CACNA1C on Behavior and Cortical Dynamics

The Impact of Overexpression of the Mouse Ortholog of CACNA1C on Behavior and Cortical Dynamics

Background: Mental disorders are common in the United States. According to the National Institute of Mental Health more than 23% of the adult population in the United States live with some form of mental illness. Genome-wide association studies have implicated CACNA1C, which encodes the L-type volta...

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Bibliographic Details
Main Authors: Rachel Parent, Ruei-Lung Lin, Lara Ouillette, Emily Glass, Hannah Burns, Michael D. Uhler, Sami L. Case, Olivier Thibault, Geoffrey G. Murphy
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Biological Psychiatry Global Open Science
Subjects:
Bipolar disorder
Cortical subnetworks
L-type calcium channel CaV1.2
Psychiatric risk variant
Schizophrenia
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174325000916
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http://www.sciencedirect.com/science/article/pii/S2667174325000916

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