Comparative Bioavailability Study of Jaspine B: Impact of Nanoliposomal Drug Delivery System on Pharmacokinetics

Comparative Bioavailability Study of Jaspine B: Impact of Nanoliposomal Drug Delivery System on Pharmacokinetics

<b>Background/Objectives</b>: Jaspine B, a synthetic analog of anhydrophytosphingosine, demonstrates significant anticancer activity; however, its clinical application is hindered by its poor oral bioavailability, resulting in suboptimal systemic exposure. This study aimed to enhance the...

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Bibliographic Details
Main Authors: Biwash Ghimire, Pradeep Giri, Sameena Mateen, Srinath Pashikanti, Ali Aghazadeh-Habashi
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Pharmaceutics
Subjects:
Jaspine B
pachastrissamine
liposomes
drug delivery
analytical method validation
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/17/7/807
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