Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment

Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment

Early-life brain injuries are major causes of long-term neurodevelopmental disorders such as cerebral palsy. Emerging evidence suggests these injuries can alter the gut microbiota composition, intestinal integrity, and neuroinflammatory responses. This systematic review evaluated the impact of early...

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Bibliographic Details
Main Authors: Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
early-life brain injury
gut microbiota
gut–brain axis
maternal inflammation
neurodevelopment
Online Access:https://www.mdpi.com/2073-4409/14/14/1063
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