Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis
Objective: to improve the results of intensive care in patients with acute lung injury in the presence of severe sepsis. Subjects and methods. Complex intensive therapy was analyzed in 87 patients with severe sepsis and acute lung injury. The patients were divided into 2 groups: 1) 43 patients treat...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-06-01
|
| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1015 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839578570138058752 |
|---|---|
| author | K. B. Grigoryev S. I. Apevalov A. E. Matyukov L. V. Okhinko |
| author_facet | K. B. Grigoryev S. I. Apevalov A. E. Matyukov L. V. Okhinko |
| author_sort | K. B. Grigoryev |
| collection | DOAJ |
| description | Objective: to improve the results of intensive care in patients with acute lung injury in the presence of severe sepsis. Subjects and methods. Complex intensive therapy was analyzed in 87 patients with severe sepsis and acute lung injury. The patients were divided into 2 groups: 1) 43 patients treated without immune-replacement therapy; 2) 44 were additionally given the intravenous immunoglobulin G Gamimun H. The laboratory parameters, mortality, and intensive care duration in an intensive care unit (ICU) were analyzed. Results. Immune-replacement therapy reduced the length of stay in the ICU from 15±5.5 to 11.5±4.4 days and mortality from 55.8 to 27.3%. Conclusion. The immunoglobulin G Gamimun (BAYER) used in patients with acute lung injury in the presence of severe sepsis has shown its high efficacy, quality, and safety. Key words: sepsis, acute lung injury, immunoglobulins, Gamimun. |
| format | Article |
| id | doaj-art-f11ce0fcdf5e4af7b4903a65b299bb9d |
| institution | Matheson Library |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2007-06-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-f11ce0fcdf5e4af7b4903a65b299bb9d2025-08-04T10:40:37ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-06-013310.15360/1813-9779-2007-3-331015Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe SepsisK. B. GrigoryevS. I. ApevalovA. E. MatyukovL. V. OkhinkoObjective: to improve the results of intensive care in patients with acute lung injury in the presence of severe sepsis. Subjects and methods. Complex intensive therapy was analyzed in 87 patients with severe sepsis and acute lung injury. The patients were divided into 2 groups: 1) 43 patients treated without immune-replacement therapy; 2) 44 were additionally given the intravenous immunoglobulin G Gamimun H. The laboratory parameters, mortality, and intensive care duration in an intensive care unit (ICU) were analyzed. Results. Immune-replacement therapy reduced the length of stay in the ICU from 15±5.5 to 11.5±4.4 days and mortality from 55.8 to 27.3%. Conclusion. The immunoglobulin G Gamimun (BAYER) used in patients with acute lung injury in the presence of severe sepsis has shown its high efficacy, quality, and safety. Key words: sepsis, acute lung injury, immunoglobulins, Gamimun.https://www.reanimatology.com/rmt/article/view/1015 |
| spellingShingle | K. B. Grigoryev S. I. Apevalov A. E. Matyukov L. V. Okhinko Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis Общая реаниматология |
| title | Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis |
| title_full | Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis |
| title_fullStr | Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis |
| title_full_unstemmed | Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis |
| title_short | Immune-Replacement Therapy in the Complex Treatment of Acute Lung Injury in Patients with Severe Sepsis |
| title_sort | immune replacement therapy in the complex treatment of acute lung injury in patients with severe sepsis |
| url | https://www.reanimatology.com/rmt/article/view/1015 |
| work_keys_str_mv | AT kbgrigoryev immunereplacementtherapyinthecomplextreatmentofacutelunginjuryinpatientswithseveresepsis AT siapevalov immunereplacementtherapyinthecomplextreatmentofacutelunginjuryinpatientswithseveresepsis AT aematyukov immunereplacementtherapyinthecomplextreatmentofacutelunginjuryinpatientswithseveresepsis AT lvokhinko immunereplacementtherapyinthecomplextreatmentofacutelunginjuryinpatientswithseveresepsis |