Method performance verification and measurement uncertainty evaluation for determination of total active matter content in shampoos
The aim of our study was to perform in-use method verification of the standard ISO 6842:1989(E) method for determination of total active matter (TAM) content in shampoos. The method was verified for accuracy and precision (method precision, repeatability and intermediate precision). To assure qualit...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association
2025-06-01
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Series: | Makedonsko Farmacevtski Bilten |
Subjects: | |
Online Access: | https://bulletin.mfd.org.mk/volumes/Volume%2071_1/71_1_007.pdf |
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Summary: | The aim of our study was to perform in-use method verification of the standard ISO 6842:1989(E) method for determination of total active matter (TAM) content in shampoos. The method was verified for accuracy and precision (method precision, repeatability and intermediate precision). To assure quality, measurement uncertainty was also estimated, through evaluation of the possible sources of uncertainty, using the Nordtest approach. The obtained results for the аccuracy, repeatability (method precision) and intermediate precision confirmed that the standard method could be successfully applied when compared to data for repeatability and intermediate precision provided in ISO 6842:1989(E) method. Measurement uncertainty was estimated for each measurement. The verified method was successfully applied for routine determination of total active matter content in shampoos.
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ISSN: | 1409-8695 1857-8969 |