Possibility of using НЕR-2/NEU & KI-67, as prognostic factors of distal stomach tumor answer for neoadjuvant therapy
From January, 1995 till December, 2002 in Dnipropetrovsk a regional clinical oncological clinic have received treatment 345 patient sick by a cancer of bottom thirds of body and antral part of a stomach. From them 91 patient has been treated by the combined method with application of remote therap...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
State Institution "Dnipro State Medical University"
2008-01-01
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| Series: | Морфологія |
| Subjects: | |
| Online Access: | http://www.morphology.dp.ua/_pub/MORPHO-2008-02-01/08dyvplt.pdf |
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| Summary: | From January, 1995 till December, 2002 in Dnipropetrovsk a regional clinical oncological clinic have received treatment 345 patient sick by a cancer of bottom thirds of body and antral part of a stomach. From them 91 patient has been treated by the combined method with application of remote therapy in a mode of an average fractioning of doze in neoadjuvant regimen. Radiotherapy was spent to patients with prevalence of tumoral process Т3N+M0 and Т4NхM0 at absence of contra-indications to carrying out of distant gamma-therapy (absolut stenosis of the gatekeeper, expressed astenia and an anemia, a bleeding from a tumour in the anamnesis). To patients with smaller prevalence of tumoral process surgical treatment was spent. In article the features of spent radiotherapy, its influence on current of tumoral process, results of surgical treatment of patients of both groups, parameters of medical pathomorphosis and their dependence on a degree of a differentiation of a tumour, parameters of lethality about one year are presented and given results of immunohistochemical researches of tumours biopsy of the patients who have received combined treatment. Also the probable interrelation between expression of НЕR-2/NEU and KI-67 with the received direct results of treatment is tracked. |
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| ISSN: | 1997-9665 |