CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN
Results of performed pre-clinical and clinical studies with volunteers 18-60 years old allowed registration of vaccine «INFLUVIR» (live monovalent vaccine for the prophylaxis of influenza A/H1N1, strain A/17/California/2009/38 (H1N1), developed by NPO «Microgen» in Russian Federation so timely vacci...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2010-07-01
|
| Series: | Вопросы современной педиатрии |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/926 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839575561366667264 |
|---|---|
| author | D.S. Bushmenkov A.N. Mironov A.A. Romanova A.A. Tsaan I.V. Feldblyum |
| author_facet | D.S. Bushmenkov A.N. Mironov A.A. Romanova A.A. Tsaan I.V. Feldblyum |
| author_sort | D.S. Bushmenkov |
| collection | DOAJ |
| description | Results of performed pre-clinical and clinical studies with volunteers 18-60 years old allowed registration of vaccine «INFLUVIR» (live monovalent vaccine for the prophylaxis of influenza A/H1N1, strain A/17/California/2009/38 (H1N1), developed by NPO «Microgen» in Russian Federation so timely vaccination campaign was performed. As a result, the level of morbidity with influenza A/H1N1 in Russia was decreased, and development of complication was prevented. Clinical studies in different groups of children were performed for the purpose of widening indications for vaccine «INFLUVIR» administration. According to the results of studies vaccine «INFLUVIR» has good tolerability and safety, low reactogenicity, and significant immunogenicity. This fact will allow changing of present normative documentation and administration of «INFLUVIR» in children of different age for prophylaxis of influenza A/H1N1.Key words: children, influenza, virus A/H1N1, live influenza vaccine, tolerability, safety, immunogenicity.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4):101-105) |
| format | Article |
| id | doaj-art-f07ccacfabdc408d90d2547ee4da36e5 |
| institution | Matheson Library |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2010-07-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-f07ccacfabdc408d90d2547ee4da36e52025-08-04T13:09:32Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352010-07-0194101105927CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREND.S. Bushmenkov0A.N. Mironov1A.A. Romanova2A.A. Tsaan3I.V. Feldblyum4NPO «Microgen», MoscowNPO «Microgen», MoscowNPO «Microgen», MoscowNPO «Microgen», MoscowYe.A. Vagner Perm State Medical AcademyResults of performed pre-clinical and clinical studies with volunteers 18-60 years old allowed registration of vaccine «INFLUVIR» (live monovalent vaccine for the prophylaxis of influenza A/H1N1, strain A/17/California/2009/38 (H1N1), developed by NPO «Microgen» in Russian Federation so timely vaccination campaign was performed. As a result, the level of morbidity with influenza A/H1N1 in Russia was decreased, and development of complication was prevented. Clinical studies in different groups of children were performed for the purpose of widening indications for vaccine «INFLUVIR» administration. According to the results of studies vaccine «INFLUVIR» has good tolerability and safety, low reactogenicity, and significant immunogenicity. This fact will allow changing of present normative documentation and administration of «INFLUVIR» in children of different age for prophylaxis of influenza A/H1N1.Key words: children, influenza, virus A/H1N1, live influenza vaccine, tolerability, safety, immunogenicity.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4):101-105)https://vsp.spr-journal.ru/jour/article/view/926 |
| spellingShingle | D.S. Bushmenkov A.N. Mironov A.A. Romanova A.A. Tsaan I.V. Feldblyum CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN Вопросы современной педиатрии |
| title | CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN |
| title_full | CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN |
| title_fullStr | CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN |
| title_full_unstemmed | CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN |
| title_short | CLINICAL STUDIES OF REACTOGENICITY, SAFETY AND IMMUNOGENICITY OF LIVE MONOVALENT INFLUENZA VACCINE (STRAIN А/17/CALIFORNIA/2009/38 — H1N1) IN CHILDREN |
| title_sort | clinical studies of reactogenicity safety and immunogenicity of live monovalent influenza vaccine strain а 17 california 2009 38 h1n1 in children |
| url | https://vsp.spr-journal.ru/jour/article/view/926 |
| work_keys_str_mv | AT dsbushmenkov clinicalstudiesofreactogenicitysafetyandimmunogenicityoflivemonovalentinfluenzavaccinestraina17california200938h1n1inchildren AT anmironov clinicalstudiesofreactogenicitysafetyandimmunogenicityoflivemonovalentinfluenzavaccinestraina17california200938h1n1inchildren AT aaromanova clinicalstudiesofreactogenicitysafetyandimmunogenicityoflivemonovalentinfluenzavaccinestraina17california200938h1n1inchildren AT aatsaan clinicalstudiesofreactogenicitysafetyandimmunogenicityoflivemonovalentinfluenzavaccinestraina17california200938h1n1inchildren AT ivfeldblyum clinicalstudiesofreactogenicitysafetyandimmunogenicityoflivemonovalentinfluenzavaccinestraina17california200938h1n1inchildren |