FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA
Preeclampsia (PE) and fetal growth restriction (FGR) are major contributors to maternal and perinatal morbidity and mortality worldwide. In Bulgaria, the burden of these conditions is compounded by delayed diagnosis and limited access to comprehensive early screening. First-trimester screening enabl...
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2025-07-01
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| Series: | Journal of IMAB |
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| Online Access: | https://www.journal-imab-bg.org/issues-2025/issue3/2025vol31-issue3_6352-6360.pdf |
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| author | Zlatko Kirovakov Elitsa Gyokova |
| author_facet | Zlatko Kirovakov Elitsa Gyokova |
| author_sort | Zlatko Kirovakov |
| collection | DOAJ |
| description | Preeclampsia (PE) and fetal growth restriction (FGR) are major contributors to maternal and perinatal morbidity and mortality worldwide. In Bulgaria, the burden of these conditions is compounded by delayed diagnosis and limited access to comprehensive early screening. First-trimester screening enables the identification of high-risk pregnancies through maternal risk factors, biomarkers, and Doppler ultrasonography. Preventive strategies, particularly the timely administration of low-dose aspirin, have proven effective in reducing the incidence of early-onset PE and FGR. This review summarizes current evidence on the pathophysiology, screening models, and prevention strategies for PE and FGR, with emphasis on their implementation in Bulgarian clinical practice. Recommendations are provided for enhancing maternal care through national policies and expanded screening programs. |
| format | Article |
| id | doaj-art-eed0fbb8dba24d4d9ebcc6f54fd00bc1 |
| institution | Matheson Library |
| issn | 1312-773X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj-art-eed0fbb8dba24d4d9ebcc6f54fd00bc12025-07-26T13:19:06ZengPeytchinski PublishingJournal of IMAB1312-773X2025-07-013136352636010.5272/jimab.2025313.6352FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIAZlatko Kirovakov0https://orcid.org/0009-0003-7643-5879Elitsa Gyokova1https://orcid.org/0000-0003-4007-7961Faculty of Public Health and Health Care, “Prof. Dr Assen Zlatarov” University, Bourgas, Bulgaria.Department of Obstetrics and Gynecology, Faculty of Medicine, Medical University – Pleven, Bulgaria.Preeclampsia (PE) and fetal growth restriction (FGR) are major contributors to maternal and perinatal morbidity and mortality worldwide. In Bulgaria, the burden of these conditions is compounded by delayed diagnosis and limited access to comprehensive early screening. First-trimester screening enables the identification of high-risk pregnancies through maternal risk factors, biomarkers, and Doppler ultrasonography. Preventive strategies, particularly the timely administration of low-dose aspirin, have proven effective in reducing the incidence of early-onset PE and FGR. This review summarizes current evidence on the pathophysiology, screening models, and prevention strategies for PE and FGR, with emphasis on their implementation in Bulgarian clinical practice. Recommendations are provided for enhancing maternal care through national policies and expanded screening programs.https://www.journal-imab-bg.org/issues-2025/issue3/2025vol31-issue3_6352-6360.pdfpreeclampsiafirst trimester screeningfetal growth restrictiongestational agepregnancy |
| spellingShingle | Zlatko Kirovakov Elitsa Gyokova FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA Journal of IMAB preeclampsia first trimester screening fetal growth restriction gestational age pregnancy |
| title | FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA |
| title_full | FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA |
| title_fullStr | FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA |
| title_full_unstemmed | FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA |
| title_short | FIRST TRIMESTER SCREENING AND PREVENTION FOR PREECLAMPSIA AND FETAL GROWTH RESTRICTION: PERSPECTIVE IN BULGARIA |
| title_sort | first trimester screening and prevention for preeclampsia and fetal growth restriction perspective in bulgaria |
| topic | preeclampsia first trimester screening fetal growth restriction gestational age pregnancy |
| url | https://www.journal-imab-bg.org/issues-2025/issue3/2025vol31-issue3_6352-6360.pdf |
| work_keys_str_mv | AT zlatkokirovakov firsttrimesterscreeningandpreventionforpreeclampsiaandfetalgrowthrestrictionperspectiveinbulgaria AT elitsagyokova firsttrimesterscreeningandpreventionforpreeclampsiaandfetalgrowthrestrictionperspectiveinbulgaria |