PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

IntroductionVaccination aims to prevent or mitigate disease by priming the immune system prior to infection. While historical vaccine development relied mostly on trial-and-error, modern approaches have become more directed. By leveraging our growing understanding of pathogen biology and immune corr...

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Bibliographic Details
Main Authors: Evan A. Elko, Charles H. D. Williamson, Heather R. Green, Marcellene A. Gates-Hollingsworth, Georgia A. Nelson, Sujata G. Pandit, Heather L. Mead, Christopher Allender, Celeste Woerle, Mark Mayo, Bart J. Currie, David P. AuCoin, John A. Altin, Paul Keim, Erik W. Settles, Jason T. Ladner
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
PepSeq
highly multiplexed serology
melioidosis
Burkholderia pseudomallei
vaccine
epitope
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1605758/full
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