Epygenetic regulation of gene expression in virus-associated human tumors
Viruses are associated with nearly 20 % of human cancers worldwide. Until recently genetic abnormalities generated by oncogenic virusesin cells were the main object of studies. Understanding of the importance of epigenetics in the regulation of gene expression prompted the investigation of virus and...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2015-06-01
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| Series: | Успехи молекулярной онкологии |
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| Online Access: | https://umo.abvpress.ru/jour/article/view/16 |
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| _version_ | 1839573488350789632 |
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| author | N. P. Kisseljova F. L. Kisseljov |
| author_facet | N. P. Kisseljova F. L. Kisseljov |
| author_sort | N. P. Kisseljova |
| collection | DOAJ |
| description | Viruses are associated with nearly 20 % of human cancers worldwide. Until recently genetic abnormalities generated by oncogenic virusesin cells were the main object of studies. Understanding of the importance of epigenetics in the regulation of gene expression prompted the investigation of virus and host interactions at the epigenetic level. We review aspects such as common futures of oncogenic virus interactions with cell epigenetic system and virus-specific peculiarities of these interactions. Knowledge of the regulation of virus genomes by cell epigenetic system and disturbances of this system by viruses should provide us with markers for following cancer progression, as well as new tools for cancer therapy |
| format | Article |
| id | doaj-art-edf037f00f7d42f9bb2c24b755e47cb3 |
| institution | Matheson Library |
| issn | 2313-805X 2413-3787 |
| language | Russian |
| publishDate | 2015-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Успехи молекулярной онкологии |
| spelling | doaj-art-edf037f00f7d42f9bb2c24b755e47cb32025-08-04T14:04:34ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872015-06-0111485510.17650/2313-805X.2014.1.1.48-5516Epygenetic regulation of gene expression in virus-associated human tumorsN. P. Kisseljova0F. L. Kisseljov1Federal State Budgetary Institution “N. N. Blokhin Russiаn Cancer Research Center”, Russian Academy of Medical Sciences, MoscowFederal State Budgetary Institution “N. N. Blokhin Russiаn Cancer Research Center”, Russian Academy of Medical Sciences, MoscowViruses are associated with nearly 20 % of human cancers worldwide. Until recently genetic abnormalities generated by oncogenic virusesin cells were the main object of studies. Understanding of the importance of epigenetics in the regulation of gene expression prompted the investigation of virus and host interactions at the epigenetic level. We review aspects such as common futures of oncogenic virus interactions with cell epigenetic system and virus-specific peculiarities of these interactions. Knowledge of the regulation of virus genomes by cell epigenetic system and disturbances of this system by viruses should provide us with markers for following cancer progression, as well as new tools for cancer therapyhttps://umo.abvpress.ru/jour/article/view/16oncogenic virusesdna methylationhistone modificationmicrorna |
| spellingShingle | N. P. Kisseljova F. L. Kisseljov Epygenetic regulation of gene expression in virus-associated human tumors Успехи молекулярной онкологии oncogenic viruses dna methylation histone modification microrna |
| title | Epygenetic regulation of gene expression in virus-associated human tumors |
| title_full | Epygenetic regulation of gene expression in virus-associated human tumors |
| title_fullStr | Epygenetic regulation of gene expression in virus-associated human tumors |
| title_full_unstemmed | Epygenetic regulation of gene expression in virus-associated human tumors |
| title_short | Epygenetic regulation of gene expression in virus-associated human tumors |
| title_sort | epygenetic regulation of gene expression in virus associated human tumors |
| topic | oncogenic viruses dna methylation histone modification microrna |
| url | https://umo.abvpress.ru/jour/article/view/16 |
| work_keys_str_mv | AT npkisseljova epygeneticregulationofgeneexpressioninvirusassociatedhumantumors AT flkisseljov epygeneticregulationofgeneexpressioninvirusassociatedhumantumors |