SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
Alkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of...
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Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
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Online Access: | https://www.pharmjournal.ru/jour/article/view/628 |
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author | T. I. Taradeyko M. V. Sidorova A. A. Iozep |
author_facet | T. I. Taradeyko M. V. Sidorova A. A. Iozep |
author_sort | T. I. Taradeyko |
collection | DOAJ |
description | Alkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of its esterification was investigated. The effect of acid concentration, reaction time and degree of carboxyethylation of the polysaccharide on the degree of esterification and the yield of the target product were shown. |
format | Article |
id | doaj-art-ec735be22baf4b9089bbfe6ad8dcdddc |
institution | Matheson Library |
issn | 2305-2066 2658-5049 |
language | Russian |
publishDate | 2019-01-01 |
publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
record_format | Article |
series | Разработка и регистрация лекарственных средств |
spelling | doaj-art-ec735be22baf4b9089bbfe6ad8dcdddc2025-08-03T19:23:55ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01041722628SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHERT. I. Taradeyko0M. V. Sidorova1A. A. Iozep2Saint-Petersburg State Chemical and Pharmaceutical UniversitySaint-Petersburg State Chemical and Pharmaceutical UniversitySaint-Petersburg State Chemical and Pharmaceutical UniversityAlkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of its esterification was investigated. The effect of acid concentration, reaction time and degree of carboxyethylation of the polysaccharide on the degree of esterification and the yield of the target product were shown.https://www.pharmjournal.ru/jour/article/view/628alginic acidcarboxyethyl alginic acidethyl ether of carboxyethyl alginic acid polymer analogous reaction |
spellingShingle | T. I. Taradeyko M. V. Sidorova A. A. Iozep SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER Разработка и регистрация лекарственных средств alginic acid carboxyethyl alginic acid ethyl ether of carboxyethyl alginic acid polymer analogous reaction |
title | SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER |
title_full | SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER |
title_fullStr | SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER |
title_full_unstemmed | SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER |
title_short | SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER |
title_sort | synthesis of carboxyethylalginic acid and its ethyl ether |
topic | alginic acid carboxyethyl alginic acid ethyl ether of carboxyethyl alginic acid polymer analogous reaction |
url | https://www.pharmjournal.ru/jour/article/view/628 |
work_keys_str_mv | AT titaradeyko synthesisofcarboxyethylalginicacidanditsethylether AT mvsidorova synthesisofcarboxyethylalginicacidanditsethylether AT aaiozep synthesisofcarboxyethylalginicacidanditsethylether |