CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION

Aim. To assess the effects of antihypertensive therapy on the dynamics of cardiometabolic risk factors among pregnant women with chronic arterial hypertension (AH) in the second trimester. Material and methods. In total, 37 pregnant women with chronic AH were examined. The clinical and anamnestic da...

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Main Author: A. V. Padyganova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2012-10-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1284
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author A. V. Padyganova
A. V. Padyganova
author_facet A. V. Padyganova
A. V. Padyganova
author_sort A. V. Padyganova
collection DOAJ
description Aim. To assess the effects of antihypertensive therapy on the dynamics of cardiometabolic risk factors among pregnant women with chronic arterial hypertension (AH) in the second trimester. Material and methods. In total, 37 pregnant women with chronic AH were examined. The clinical and anamnestic data were analysed, and the levels of office blood pressure, body mass index, blood lipids, systemic inflammation markers (C-reactive protein, fibrinogen), and glucose were measured. Subclinical pathology of target organs was assessed via the measurement of left ventricular myocardial mass index (echocardiography), glomerular filtration rate, and microalbuminuria. Results. Slow-release nifedipine therapy improved the parameters of lipid metabolism and target organ status. Metoprolol therapy was linked to an improvement in cardiovascular and renal structure and function. However, metildopa treatment was associated with some increase in glucose levels and a significant elevation in total cholesterol levels. Conclusion. The complex assessment of cardiometabolic risk factors and target organ status is particularly important for a differential choice of antihypertensive therapy in pregnant women.
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spelling doaj-art-ec4eaae902df45c2a75c6206e10acac02025-08-04T13:00:07Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202012-10-010575801079CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSIONA. V. Padyganova0A. V. Padyganova1Kirov State Medical Academy, KirovKirov State Medical Academy, KirovAim. To assess the effects of antihypertensive therapy on the dynamics of cardiometabolic risk factors among pregnant women with chronic arterial hypertension (AH) in the second trimester. Material and methods. In total, 37 pregnant women with chronic AH were examined. The clinical and anamnestic data were analysed, and the levels of office blood pressure, body mass index, blood lipids, systemic inflammation markers (C-reactive protein, fibrinogen), and glucose were measured. Subclinical pathology of target organs was assessed via the measurement of left ventricular myocardial mass index (echocardiography), glomerular filtration rate, and microalbuminuria. Results. Slow-release nifedipine therapy improved the parameters of lipid metabolism and target organ status. Metoprolol therapy was linked to an improvement in cardiovascular and renal structure and function. However, metildopa treatment was associated with some increase in glucose levels and a significant elevation in total cholesterol levels. Conclusion. The complex assessment of cardiometabolic risk factors and target organ status is particularly important for a differential choice of antihypertensive therapy in pregnant women.https://russjcardiol.elpub.ru/jour/article/view/1284key words: cardiometabolic risk, pregnancy, chronic arterial hypertension
spellingShingle A. V. Padyganova
A. V. Padyganova
CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
Российский кардиологический журнал
key words: cardiometabolic risk, pregnancy, chronic arterial hypertension
title CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
title_full CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
title_fullStr CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
title_full_unstemmed CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
title_short CARDIOMETABOLIC RISK AND MODERN METHODS OF ITS CORRECTION IN PREGNANT WOMEN WITH CHRONIC ARTERIAL HYPERTENSION
title_sort cardiometabolic risk and modern methods of its correction in pregnant women with chronic arterial hypertension
topic key words: cardiometabolic risk, pregnancy, chronic arterial hypertension
url https://russjcardiol.elpub.ru/jour/article/view/1284
work_keys_str_mv AT avpadyganova cardiometabolicriskandmodernmethodsofitscorrectioninpregnantwomenwithchronicarterialhypertension
AT avpadyganova cardiometabolicriskandmodernmethodsofitscorrectioninpregnantwomenwithchronicarterialhypertension