Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review

Abstract Purpose Cemented unicompartmental knee arthroplasty (UKA) is a widely used procedure in the treatment of anteromedial and lateral knee osteoarthritis. However, several advantages are reported for cementless UKA, such as improved osseointegration, reduced cement‐related costs and complicatio...

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Main Authors: Pierangelo Za, Giuseppe Francesco Papalia, Umberto Cardile, Pietro Gregori, Sebastiano Vasta, Edoardo Franceschetti, Stefano Campi, Rocco Papalia
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of Experimental Orthopaedics
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Online Access:https://doi.org/10.1002/jeo2.70253
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author Pierangelo Za
Giuseppe Francesco Papalia
Umberto Cardile
Pietro Gregori
Sebastiano Vasta
Edoardo Franceschetti
Stefano Campi
Rocco Papalia
author_facet Pierangelo Za
Giuseppe Francesco Papalia
Umberto Cardile
Pietro Gregori
Sebastiano Vasta
Edoardo Franceschetti
Stefano Campi
Rocco Papalia
author_sort Pierangelo Za
collection DOAJ
description Abstract Purpose Cemented unicompartmental knee arthroplasty (UKA) is a widely used procedure in the treatment of anteromedial and lateral knee osteoarthritis. However, several advantages are reported for cementless UKA, such as improved osseointegration, reduced cement‐related costs and complications. The aim of this study was to analyse clinical outcomes, survival, complications, failures and revision rate of cementless UKA. Methods A systematic review was performed on 31 May 2024, on PubMed, Cochrane Library and Scopus. We included randomised clinical trials and prospective and retrospective studies reporting clinical outcomes, implant survival, complications, failures and revision rates of cementless UKA. The following data were extracted: study design, type of implant, number of patients and knees, follow‐up, age, sex, pre‐operative and post‐operative clinical outcomes, reoperations and revisions with causes of failure and overall survival. Results Fifteen studies were included, involving 3475 patients and 3641 UKA (2568 cementless UKA and 854 cemented UKA). The mean patients' age was 66 years. The mean follow‐up was 6.5 years. The Oxford Knee Score improved from 17.8 preoperatively to 40.3 post‐operatively in cementless UKA. Knee Society Score improved from 118.2 preoperatively to 168.6 post‐operatively in cementless UKA. The reoperation rate was 3.85% for cementless UKA and 9% for cemented UKA. The most common causes of revision were osteoarthritis progression (1.4%), aseptic loosening (0.8%), bearing dislocation and unexplained pain (0.7%). The overall survival of cementless UKA was 96.2% and 93.6% at 5 and 10 years, respectively. Conclusion Cementless UKA is a viable alternative to cemented UKAs with a low failure rate, without a lower clinical benefit at a minimum follow‐up of 4.2 years. Level of Evidence Level III, systematic review of studies.
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spelling doaj-art-eb4f5dffcfd34065a3d6e80bb9ec5d962025-06-30T13:46:48ZengWileyJournal of Experimental Orthopaedics2197-11532025-04-01122n/an/a10.1002/jeo2.70253Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic reviewPierangelo Za0Giuseppe Francesco Papalia1Umberto Cardile2Pietro Gregori3Sebastiano Vasta4Edoardo Franceschetti5Stefano Campi6Rocco Papalia7Department of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyDepartment of Orthopaedic and Trauma Surgery Università Campus Bio‐Medico di Roma Roma ItalyAbstract Purpose Cemented unicompartmental knee arthroplasty (UKA) is a widely used procedure in the treatment of anteromedial and lateral knee osteoarthritis. However, several advantages are reported for cementless UKA, such as improved osseointegration, reduced cement‐related costs and complications. The aim of this study was to analyse clinical outcomes, survival, complications, failures and revision rate of cementless UKA. Methods A systematic review was performed on 31 May 2024, on PubMed, Cochrane Library and Scopus. We included randomised clinical trials and prospective and retrospective studies reporting clinical outcomes, implant survival, complications, failures and revision rates of cementless UKA. The following data were extracted: study design, type of implant, number of patients and knees, follow‐up, age, sex, pre‐operative and post‐operative clinical outcomes, reoperations and revisions with causes of failure and overall survival. Results Fifteen studies were included, involving 3475 patients and 3641 UKA (2568 cementless UKA and 854 cemented UKA). The mean patients' age was 66 years. The mean follow‐up was 6.5 years. The Oxford Knee Score improved from 17.8 preoperatively to 40.3 post‐operatively in cementless UKA. Knee Society Score improved from 118.2 preoperatively to 168.6 post‐operatively in cementless UKA. The reoperation rate was 3.85% for cementless UKA and 9% for cemented UKA. The most common causes of revision were osteoarthritis progression (1.4%), aseptic loosening (0.8%), bearing dislocation and unexplained pain (0.7%). The overall survival of cementless UKA was 96.2% and 93.6% at 5 and 10 years, respectively. Conclusion Cementless UKA is a viable alternative to cemented UKAs with a low failure rate, without a lower clinical benefit at a minimum follow‐up of 4.2 years. Level of Evidence Level III, systematic review of studies.https://doi.org/10.1002/jeo2.70253cemented knee replacementscementless knee replacementsclinical outcomesrevisionssurvivorshipunicompartmental knee arthroplasty
spellingShingle Pierangelo Za
Giuseppe Francesco Papalia
Umberto Cardile
Pietro Gregori
Sebastiano Vasta
Edoardo Franceschetti
Stefano Campi
Rocco Papalia
Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
Journal of Experimental Orthopaedics
cemented knee replacements
cementless knee replacements
clinical outcomes
revisions
survivorship
unicompartmental knee arthroplasty
title Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
title_full Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
title_fullStr Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
title_full_unstemmed Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
title_short Cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow‐up of 4.2 years: A systematic review
title_sort cementless unicompartmental knee arthroplasty is safe and effective at a minimum follow up of 4 2 years a systematic review
topic cemented knee replacements
cementless knee replacements
clinical outcomes
revisions
survivorship
unicompartmental knee arthroplasty
url https://doi.org/10.1002/jeo2.70253
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