Application of therapeutic nucleic acids and RNA interference to create products for personalised medicine

INTRODUCTION. Small interfering RNAs (siRNAs) are among the most promising types of therapeutic nucleic acids aiming at the inhibition of pathogenetically relevant gene expression through the RNA interference mechanism. However, the limited bioavailability and immunogenicity of siRNAs and imperfect...

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Hauptverfasser:	I. P. Shilovskiy, G. B. Pasikhov, V. V. Smirnov, I. A. Kofiadi, M. V. Popova, P. A. Strueva, M. R. Khaitov
Format:	Artikel
Sprache:	Russisch
Veröffentlicht:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-07-01
Schriftenreihe:	Биопрепараты: Профилактика, диагностика, лечение
Schlagworte:	therapeutic nucleic acids rna interference small interfering rna sirna personalised medicine rna delivery systems galnac cell-penetrating peptides clinical trials safety of sirna medicinal products efficacy of sirna medicinal products
Online-Zugang:	https://www.biopreparations.ru/jour/article/view/575
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Application of therapeutic nucleic acids and RNA interference to create products for personalised medicine

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