Overexpression of GDF15 protects kidneys from ischemia reperfusion injury and affects circular RNA expression

Overexpression of GDF15 protects kidneys from ischemia reperfusion injury and affects circular RNA expression

BackgroundRenal failure and dysfunction remain one of the most significant morbidities impacting patient’s life. Effective treatments still lack in the context of an increasing number of patients with renal failure. This study aims to investigate the impact of growth differentiation factor 15 (GDF15...

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Bibliographic Details
Main Authors: Cuilin Zhu, Qing Liu, Yale Su, Yixin Zhang, Aanal Patel, Adam Greasley, Jifu Jiang, Douglas Quan, Weiping Min, Kexiang Liu, Xiufen Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GDF15
ischemia reperfusion injury
kidney
apoptosis
inflammation
circular RNA
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1577625/full
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