Giant ameloblastoma of the mandible
Ameloblastoma is a benign odontogenic tumor characterized by slow, asymptomatic growth and local aggressiveness. We report a case of a 24-year-old female with a gradually enlarging, painless swelling on the left side of her mandible over 3 years. Imaging revealed a 12 × 8 cm multilocular radiolucent...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325005254 |
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| author | Pranjal Rai, MD Fabien Necker, MD Animesh Awadhiya, MBBS Joe Joseph, MD Dhairya A. Lakhani, MD |
| author_facet | Pranjal Rai, MD Fabien Necker, MD Animesh Awadhiya, MBBS Joe Joseph, MD Dhairya A. Lakhani, MD |
| author_sort | Pranjal Rai, MD |
| collection | DOAJ |
| description | Ameloblastoma is a benign odontogenic tumor characterized by slow, asymptomatic growth and local aggressiveness. We report a case of a 24-year-old female with a gradually enlarging, painless swelling on the left side of her mandible over 3 years. Imaging revealed a 12 × 8 cm multilocular radiolucent lesion with cortical thinning and perforation, extending from the premolar to the angle of the mandibular ramus. Differential diagnoses included odontogenic keratocyst, dentigerous cyst, and other radiolucent mandibular lesions, and histopathological analysis confirmed a solid/multicystic ameloblastoma. The patient underwent segmental mandibulectomy with immediate reconstruction using a free fibular flap. Postoperative recovery was uneventful, and no recurrence was observed during one year of follow-up. This case highlights the importance of early recognition of asymptomatic jaw swellings, integration of imaging and histology for diagnosis, and radical surgical management for extensive lesions. Prompt intervention can reduce morbidity and optimize long-term outcomes in young patients. |
| format | Article |
| id | doaj-art-ea85bd588abf4bd28a3b51f3bc980c2b |
| institution | Matheson Library |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-ea85bd588abf4bd28a3b51f3bc980c2b2025-07-13T04:54:01ZengElsevierRadiology Case Reports1930-04332025-09-0120946004603Giant ameloblastoma of the mandiblePranjal Rai, MD0Fabien Necker, MD1Animesh Awadhiya, MBBS2Joe Joseph, MD3Dhairya A. Lakhani, MD4Department of Radiology, Tata Memorial Hospital, Mumbai, India; Corresponding author.Digital Anatomy Lab, Institute for Functional and Clinical Anatomy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, GermanyDepartment of Radiology, Tata Memorial Hospital, Mumbai, IndiaDepartment of Neuroradiology, West Virginia University, Morgantown, WV, USADepartment of Neuroradiology, West Virginia University, Morgantown, WV, USAAmeloblastoma is a benign odontogenic tumor characterized by slow, asymptomatic growth and local aggressiveness. We report a case of a 24-year-old female with a gradually enlarging, painless swelling on the left side of her mandible over 3 years. Imaging revealed a 12 × 8 cm multilocular radiolucent lesion with cortical thinning and perforation, extending from the premolar to the angle of the mandibular ramus. Differential diagnoses included odontogenic keratocyst, dentigerous cyst, and other radiolucent mandibular lesions, and histopathological analysis confirmed a solid/multicystic ameloblastoma. The patient underwent segmental mandibulectomy with immediate reconstruction using a free fibular flap. Postoperative recovery was uneventful, and no recurrence was observed during one year of follow-up. This case highlights the importance of early recognition of asymptomatic jaw swellings, integration of imaging and histology for diagnosis, and radical surgical management for extensive lesions. Prompt intervention can reduce morbidity and optimize long-term outcomes in young patients.http://www.sciencedirect.com/science/article/pii/S1930043325005254AmeloblastomaOdontogenic tumorsBone tumorsMandibular neoplasmsJaw reconstruction |
| spellingShingle | Pranjal Rai, MD Fabien Necker, MD Animesh Awadhiya, MBBS Joe Joseph, MD Dhairya A. Lakhani, MD Giant ameloblastoma of the mandible Radiology Case Reports Ameloblastoma Odontogenic tumors Bone tumors Mandibular neoplasms Jaw reconstruction |
| title | Giant ameloblastoma of the mandible |
| title_full | Giant ameloblastoma of the mandible |
| title_fullStr | Giant ameloblastoma of the mandible |
| title_full_unstemmed | Giant ameloblastoma of the mandible |
| title_short | Giant ameloblastoma of the mandible |
| title_sort | giant ameloblastoma of the mandible |
| topic | Ameloblastoma Odontogenic tumors Bone tumors Mandibular neoplasms Jaw reconstruction |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325005254 |
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