Mechanism of action of total saponin Achyranthes in treating knee osteoarthritis explored using network pharmacology and animal experimentation

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Mechanism of action of total saponin Achyranthes in treating knee osteoarthritis explored using network pharmacology and animal experimentation

Objective(s): Knee osteoarthritis (KOA) is a persistent degenerative disease affecting the joints, significantly reducing the quality of life for individuals afflicted. This study explores the therapeutic effects of total saponin Achranthes (TSA) on KOA rats and its underlying mechanism. Materials...

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Bibliographic Details
Main Authors:	Shiwei Zhuang, Qiang Chen, Xiao Guo, Wenhai Zhao, Ye Qiu
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2025-06-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	achyranthes knee osteoarthritis anti-inflammatory pharmacology rats matrix metalloproteinase 9
Online Access:	https://ijbms.mums.ac.ir/article_25684_49e9fec74146e518ad0af3a0a3ba0ffb.pdf
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