Selective blockade of acid-sensing ion channel 1a can provide substantial hippocampal neuroprotection

Selective blockade of acid-sensing ion channel 1a can provide substantial hippocampal neuroprotection

BackgroundAcid-sensing ion channel 1a (ASIC1a) is the only member of the ASIC family where Ca2+ osmosis has been reported, and it is highly expressed in neurons of the central nervous system. This study aimed to investigate whether ASIC1a is trafficked to the plasma membrane and regulated by the Rho...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiaai Li, Yu Cheng, Di Ma, Guangjian Li, Weixuan Zhao, Ting Jiang, Hongmei Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ASIC1a
temporal lobe epilepsy
neuroprotection
hippocampus
Rho/ROCK
PI3K
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1582970/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items