TLR9 gene polymorphism -1237T/C (rs5743836) is associated with low IgG antibody response against PvCSP variants in symptomatic P. vivax infections in Venezuela.
<h4>Background</h4>Clinical immunity to malaria has been associated with humoral immune responses targeting asexual-stage parasite proteins. However, the variability in antibody-driven responses may be influenced by genetic factors in the human host. This study aimed to evaluate the freq...
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Main Authors: | Fhabián S Carrión-Nessi, Eva Salazar-Alcalá, David A Forero-Peña, Kellys A Curiel, Mary Lopez-Perez, Mercedes Fernández-Mestre |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-06-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0013262 |
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