Study on the Antimicrobial Properties of Surface-Modified Dental Implants
Background: Dental implants have revolutionized restorative dentistry, but peri-implantitis caused by bacterial colonization remains a significant challenge. Surface modification of implants has emerged as a promising strategy to enhance their antimicrobial properties, ensuring better long-term outc...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
Wolters Kluwer Medknow Publications
2025-06-01
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| श्रृंखला: | Journal of Pharmacy and Bioallied Sciences |
| विषय: | |
| ऑनलाइन पहुंच: | https://journals.lww.com/10.4103/jpbs.jpbs_105_25 |
| टैग: |
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| सारांश: | Background:
Dental implants have revolutionized restorative dentistry, but peri-implantitis caused by bacterial colonization remains a significant challenge. Surface modification of implants has emerged as a promising strategy to enhance their antimicrobial properties, ensuring better long-term outcomes. This study evaluates the antimicrobial efficacy of surface-modified dental implants against common oral pathogens.
Materials and Methods:
Thirty dental implants were divided into three groups: Group A (unmodified titanium implants), Group B (titanium implants coated with silver nanoparticles), and Group C (titanium implants coated with zinc oxide nanoparticles). The antimicrobial activity of each group was assessed using an agar diffusion test against Streptococcus mutans and Porphyromonas gingivalis. Colony-forming units (CFUs) were counted after 48 hours of incubation. Statistical analysis was performed using ANOVA to compare the antimicrobial efficacy between groups, with a significance level set at P < 0.05.
Results:
Group A showed minimal antimicrobial activity, with mean inhibition zones of 1.5 ± 0.3 mm for S. mutans and 1.2 ± 0.4 mm for P. gingivalis. Group B exhibited significantly higher antimicrobial activity, with mean inhibition zones of 10.5 ± 0.8 mm for S. mutans and 9.3 ± 0.7 mm for P. gingivalis (P < 0.05). Group C demonstrated moderate activity, with inhibition zones of 6.8 ± 0.5 mm for S. mutans and 5.9 ± 0.6 mm for P. gingivalis. The reduction in CFUs followed a similar trend, with Group B showing the highest reduction.
Conclusion:
Surface-modified dental implants, particularly those coated with silver nanoparticles, exhibit enhanced antimicrobial properties compared to unmodified implants. This suggests that incorporating antimicrobial coatings can be a viable strategy to reduce peri-implantitis and improve implant success rates. Further in vivo studies are recommended to validate these findings. |
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