The effect of using nanoparticles in bioactive glass on its antimicrobial properties

ObjectivesThis study addresses the effect of using nanoparticles (np) on the antimicrobial properties of bioactive glass (BAG) when used in intracanal medicaments against Enterococcus faecalis (E. faecalis) biofilms.Materials and MethodsE. faecalis biofilms, grown inside 90 root canals for 21 days,...

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Main Authors: Maram Farouk Obeid, Kareim Moustafa El-Batouty, Mohammed Aslam
Format: Article
Sprog:engelsk
Udgivet: Korean Academy of Conservative Dentistry 2021-11-01
Serier:Restorative Dentistry & Endodontics
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Online adgang:http://rde.ac/upload/pdf/rde-46-e58.pdf
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author Maram Farouk Obeid
Kareim Moustafa El-Batouty
Mohammed Aslam
author_facet Maram Farouk Obeid
Kareim Moustafa El-Batouty
Mohammed Aslam
author_sort Maram Farouk Obeid
collection DOAJ
description ObjectivesThis study addresses the effect of using nanoparticles (np) on the antimicrobial properties of bioactive glass (BAG) when used in intracanal medicaments against Enterococcus faecalis (E. faecalis) biofilms.Materials and MethodsE. faecalis biofilms, grown inside 90 root canals for 21 days, were randomly divided into 4 groups according to the antimicrobial regimen followed (n = 20; BAG-np, BAG, calcium hydroxide [CaOH], and saline). After 1 week, residual live bacteria were quantified in terms of colony-forming units (CFU), while dead bacteria were assessed with a confocal laser scanning microscope.ResultsAlthough there was a statistically significant decrease in the mean CFU value among all groups, the nano-group performed the best. The highest percentage of dead bacteria was detected in the BAG-np group, with a significant difference from the BAG group.ConclusionsThe reduction of particle size and use of a nano-form of BAG improved the antimicrobial properties of the intracanal treatment of E. faecalis biofilms
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publishDate 2021-11-01
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series Restorative Dentistry & Endodontics
spelling doaj-art-e893e419c9b54697a4d1b0ea657ba2942025-07-03T04:25:09ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662021-11-01464e5810.5395/rde.2021.46.e58998The effect of using nanoparticles in bioactive glass on its antimicrobial propertiesMaram Farouk Obeid0Kareim Moustafa El-Batouty1Mohammed Aslam2Department of Endodontic, Faculty of Dentistry, Ain Shams University, Cairo, EgyptDepartment of Endodontic, Faculty of Dentistry, Ain Shams University, Cairo, EgyptDepartment of Endodontic, Faculty of Dentistry, Ain Shams University, Cairo, EgyptObjectivesThis study addresses the effect of using nanoparticles (np) on the antimicrobial properties of bioactive glass (BAG) when used in intracanal medicaments against Enterococcus faecalis (E. faecalis) biofilms.Materials and MethodsE. faecalis biofilms, grown inside 90 root canals for 21 days, were randomly divided into 4 groups according to the antimicrobial regimen followed (n = 20; BAG-np, BAG, calcium hydroxide [CaOH], and saline). After 1 week, residual live bacteria were quantified in terms of colony-forming units (CFU), while dead bacteria were assessed with a confocal laser scanning microscope.ResultsAlthough there was a statistically significant decrease in the mean CFU value among all groups, the nano-group performed the best. The highest percentage of dead bacteria was detected in the BAG-np group, with a significant difference from the BAG group.ConclusionsThe reduction of particle size and use of a nano-form of BAG improved the antimicrobial properties of the intracanal treatment of E. faecalis biofilmshttp://rde.ac/upload/pdf/rde-46-e58.pdfbioactive glassbiofilmconfocal laser scanning microscopynanoparticles
spellingShingle Maram Farouk Obeid
Kareim Moustafa El-Batouty
Mohammed Aslam
The effect of using nanoparticles in bioactive glass on its antimicrobial properties
Restorative Dentistry & Endodontics
bioactive glass
biofilm
confocal laser scanning microscopy
nanoparticles
title The effect of using nanoparticles in bioactive glass on its antimicrobial properties
title_full The effect of using nanoparticles in bioactive glass on its antimicrobial properties
title_fullStr The effect of using nanoparticles in bioactive glass on its antimicrobial properties
title_full_unstemmed The effect of using nanoparticles in bioactive glass on its antimicrobial properties
title_short The effect of using nanoparticles in bioactive glass on its antimicrobial properties
title_sort effect of using nanoparticles in bioactive glass on its antimicrobial properties
topic bioactive glass
biofilm
confocal laser scanning microscopy
nanoparticles
url http://rde.ac/upload/pdf/rde-46-e58.pdf
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