Blood lipid profile and cardiovascular disease in family history among young people with various health status
Aim. To study blood lipid profile and cardiovascular disease (CVD) in family history of young people with various health status. Material and methods. The study included 80 people aged 18-29 (mean age 22.3±0.4 years). In all participants, health status screening was performed. According to adaptatio...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2005-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1044 |
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| Summary: | Aim. To study blood lipid profile and cardiovascular disease (CVD) in family history of young people with various health status. Material and methods. The study included 80 people aged 18-29 (mean age 22.3±0.4 years). In all participants, health status screening was performed. According to adaptation potential level, three groups were identified: with good (I), fair (II), and poor (III) adaptation potential. The following parameters of lipidogram were registered: total cholesterol (TCH), high-density lipoprotein cholesterol (HDL-CH), low- and very low-density lipoprotein cholesterol (LDL-CH, VLDL-CH), triglycerides (TG); atherogenicity index (AI) was also calculated. In participants with dyslipoproteinemia (DLP), detailed information on CVD in family history was collected. Results. Adaptation potential was reduced in 56 persons (70%). Abnormal lipidogram (TCH >5.88 mmol/l, LDLCH >3.83 mol/l, and AI >3 U) was observed in 4 participants from Group III (19%), including 3 individuals (14.3%) with TG >1.75 mmol/l (equivalent of Type IIa and III DLP). For all three groups, differences in TCH, LDL-CH, and AI levels were statistically significant. Conclusion. Even in young people, initial symptoms of lipid metabolism abnormality were detected, including hyper- and dyslipidemia. Abnormal lipid metabolism was observed only in young males with poor adaptation potential. Participants with disturbed lipid metabolism had CVD in family history. |
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| ISSN: | 1728-8800 2619-0125 |