A paradigm shift in simulating affinity maturation to elicit broadly neutralizing antibodies

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A paradigm shift in simulating affinity maturation to elicit broadly neutralizing antibodies

Broadly neutralizing antibodies (bnAbs) offer a promising route to protect against rapidly evolving pathogens such as HIV, influenza, and SARS-CoV-2, yet eliciting them through vaccination remains a significant challenge. A key to this problem lies in understanding antibody affinity maturation (AM),...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Fahsai Nakarin, Kayla G. Sprenger
Μορφή:	Άρθρο
Γλώσσα:	Αγγλικά
Έκδοση:	Frontiers Media S.A. 2025-07-01
Σειρά:	Frontiers in Immunology
Θέματα:	affinity maturation germinal center simulation broadly neutralizing antibody B cell
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1627674/full
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

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