OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE
Objective: in women over 35 years of age, there is a progressive and age-related decline in fertility, which is due to multiple consequences, including a decrease in follicular reserve. Cytokines play a role, mediating the interaction between oocytes and other cells. In addition, there is a change i...
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| Format: | Article |
| Language: | English |
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2020-03-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/1037 |
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| author | K. V. Uryupina I. I. Kutsenko E. I. Kravtsova P. A. Gavryuchenko |
| author_facet | K. V. Uryupina I. I. Kutsenko E. I. Kravtsova P. A. Gavryuchenko |
| author_sort | K. V. Uryupina |
| collection | DOAJ |
| description | Objective: in women over 35 years of age, there is a progressive and age-related decline in fertility, which is due to multiple consequences, including a decrease in follicular reserve. Cytokines play a role, mediating the interaction between oocytes and other cells. In addition, there is a change in the expression of mRNA of a number of genes, leading to a decrease in the ability to bear children. The goal is to highlight the problem of reducing fertility in women of older reproductive age. Materials and methods: medLine, Pubmed, RISC, etc. Results: analysis of literature data shows that fertility decline is determined by a combination of physiological, molecular and genetic factors that play an increasing role as we age.Conclusion: the development of modern technology can solve the problem of infertility in the vast majority of cases. However, the lack of effectiveness of assisted reproductive technologies (ART) for women over 35 years of age requires optimizing a care strategy for these women. |
| format | Article |
| id | doaj-art-e8226bd9daf043cf857a5128ca597712 |
| institution | Matheson Library |
| issn | 2219-8075 2618-7876 |
| language | English |
| publishDate | 2020-03-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj-art-e8226bd9daf043cf857a5128ca5977122025-07-03T16:13:39ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762020-03-01111142010.21886/2219-8075-2020-11-1-14-20552OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGEK. V. Uryupina0I. I. Kutsenko1E. I. Kravtsova2P. A. Gavryuchenko3Kuban state medical UniversityKuban state medical UniversityKuban state medical UniversityKuban state medical UniversityObjective: in women over 35 years of age, there is a progressive and age-related decline in fertility, which is due to multiple consequences, including a decrease in follicular reserve. Cytokines play a role, mediating the interaction between oocytes and other cells. In addition, there is a change in the expression of mRNA of a number of genes, leading to a decrease in the ability to bear children. The goal is to highlight the problem of reducing fertility in women of older reproductive age. Materials and methods: medLine, Pubmed, RISC, etc. Results: analysis of literature data shows that fertility decline is determined by a combination of physiological, molecular and genetic factors that play an increasing role as we age.Conclusion: the development of modern technology can solve the problem of infertility in the vast majority of cases. However, the lack of effectiveness of assisted reproductive technologies (ART) for women over 35 years of age requires optimizing a care strategy for these women.https://www.medicalherald.ru/jour/article/view/1037infertility, art, oocytes, review |
| spellingShingle | K. V. Uryupina I. I. Kutsenko E. I. Kravtsova P. A. Gavryuchenko OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE Медицинский вестник Юга России infertility, art, oocytes, review |
| title | OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE |
| title_full | OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE |
| title_fullStr | OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE |
| title_full_unstemmed | OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE |
| title_short | OVARIAN INFERTILITY FACTOR IN PATIENTS OF LATE REPRODUCTIVE AGE |
| title_sort | ovarian infertility factor in patients of late reproductive age |
| topic | infertility, art, oocytes, review |
| url | https://www.medicalherald.ru/jour/article/view/1037 |
| work_keys_str_mv | AT kvuryupina ovarianinfertilityfactorinpatientsoflatereproductiveage AT iikutsenko ovarianinfertilityfactorinpatientsoflatereproductiveage AT eikravtsova ovarianinfertilityfactorinpatientsoflatereproductiveage AT pagavryuchenko ovarianinfertilityfactorinpatientsoflatereproductiveage |