Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
Intra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentiall...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2025-06-01
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Series: | Indian Journal of Ophthalmology |
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Online Access: | https://journals.lww.com/10.4103/IJO.IJO_2912_24 |
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author | Pallav Bhatter Rajsrinivas Parthasarathy Vipul Gupta Srinivas Rao Dusa Ujjwal Aggarwal Sima Das Pallav Kumar |
author_facet | Pallav Bhatter Rajsrinivas Parthasarathy Vipul Gupta Srinivas Rao Dusa Ujjwal Aggarwal Sima Das Pallav Kumar |
author_sort | Pallav Bhatter |
collection | DOAJ |
description | Intra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentially avoiding the need for enucleation. Nevertheless, procedure-related complications have raised concerns. In this article, we outline the various technical considerations for performing safe IAC and minimizing procedure-related complications. |
format | Article |
id | doaj-art-e7de94da5f3547728d78a66a87bb5c68 |
institution | Matheson Library |
issn | 0301-4738 1998-3689 |
language | English |
publishDate | 2025-06-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Ophthalmology |
spelling | doaj-art-e7de94da5f3547728d78a66a87bb5c682025-07-04T07:45:15ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-06-0173691691910.4103/IJO.IJO_2912_24Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?Pallav BhatterRajsrinivas ParthasarathyVipul GuptaSrinivas Rao DusaUjjwal AggarwalSima DasPallav KumarIntra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentially avoiding the need for enucleation. Nevertheless, procedure-related complications have raised concerns. In this article, we outline the various technical considerations for performing safe IAC and minimizing procedure-related complications.https://journals.lww.com/10.4103/IJO.IJO_2912_24intraarterial chemotherapyophthalmic arteryretinoblastoma |
spellingShingle | Pallav Bhatter Rajsrinivas Parthasarathy Vipul Gupta Srinivas Rao Dusa Ujjwal Aggarwal Sima Das Pallav Kumar Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? Indian Journal of Ophthalmology intraarterial chemotherapy ophthalmic artery retinoblastoma |
title | Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? |
title_full | Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? |
title_fullStr | Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? |
title_full_unstemmed | Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? |
title_short | Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know? |
title_sort | do s and don ts for intraarterial chemotherapy for retinoblastoma what ophthalmologist and interventional radiologist need to know |
topic | intraarterial chemotherapy ophthalmic artery retinoblastoma |
url | https://journals.lww.com/10.4103/IJO.IJO_2912_24 |
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