Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?

Intra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentiall...

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Main Authors: Pallav Bhatter, Rajsrinivas Parthasarathy, Vipul Gupta, Srinivas Rao Dusa, Ujjwal Aggarwal, Sima Das, Pallav Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-06-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/IJO.IJO_2912_24
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author Pallav Bhatter
Rajsrinivas Parthasarathy
Vipul Gupta
Srinivas Rao Dusa
Ujjwal Aggarwal
Sima Das
Pallav Kumar
author_facet Pallav Bhatter
Rajsrinivas Parthasarathy
Vipul Gupta
Srinivas Rao Dusa
Ujjwal Aggarwal
Sima Das
Pallav Kumar
author_sort Pallav Bhatter
collection DOAJ
description Intra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentially avoiding the need for enucleation. Nevertheless, procedure-related complications have raised concerns. In this article, we outline the various technical considerations for performing safe IAC and minimizing procedure-related complications.
format Article
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institution Matheson Library
issn 0301-4738
1998-3689
language English
publishDate 2025-06-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Ophthalmology
spelling doaj-art-e7de94da5f3547728d78a66a87bb5c682025-07-04T07:45:15ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-06-0173691691910.4103/IJO.IJO_2912_24Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?Pallav BhatterRajsrinivas ParthasarathyVipul GuptaSrinivas Rao DusaUjjwal AggarwalSima DasPallav KumarIntra-arterial chemotherapy (IAC) has emerged as the primary treatment option for retinoblastoma management. It enables the localized delivery of a higher concentration of chemotherapeutic agents (melphalan, carboplatin and topotecan) in the ophthalmic artery, enhancing tumour control and potentially avoiding the need for enucleation. Nevertheless, procedure-related complications have raised concerns. In this article, we outline the various technical considerations for performing safe IAC and minimizing procedure-related complications.https://journals.lww.com/10.4103/IJO.IJO_2912_24intraarterial chemotherapyophthalmic arteryretinoblastoma
spellingShingle Pallav Bhatter
Rajsrinivas Parthasarathy
Vipul Gupta
Srinivas Rao Dusa
Ujjwal Aggarwal
Sima Das
Pallav Kumar
Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
Indian Journal of Ophthalmology
intraarterial chemotherapy
ophthalmic artery
retinoblastoma
title Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
title_full Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
title_fullStr Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
title_full_unstemmed Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
title_short Do’s and Don’ts” for intraarterial chemotherapy for retinoblastoma- What ophthalmologist and interventional radiologist need to know?
title_sort do s and don ts for intraarterial chemotherapy for retinoblastoma what ophthalmologist and interventional radiologist need to know
topic intraarterial chemotherapy
ophthalmic artery
retinoblastoma
url https://journals.lww.com/10.4103/IJO.IJO_2912_24
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