Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test

Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a global pandemic and is now the most threatening public health issue. Patients with the infection present with high fever and pneumonia with respiratory symptoms, but some patients also develop diges...

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Main Authors: Sung Hoon Jung, Jung Hwan Oh
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2020-06-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://www.helicojournal.org/upload/pdf/kjhugr-2020-0030.pdf
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author Sung Hoon Jung
Jung Hwan Oh
author_facet Sung Hoon Jung
Jung Hwan Oh
author_sort Sung Hoon Jung
collection DOAJ
description Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a global pandemic and is now the most threatening public health issue. Patients with the infection present with high fever and pneumonia with respiratory symptoms, but some patients also develop digestive symptoms such as diarrhea, vomiting, and abdominal pain. This may be the basis for the transmission route of the new virus, not only for respiratory infection through droplets but also for fecal-to-oral transmission. In addition, the high expression level of angiotensin-converting enzyme 2 on the surface cells in the gastrointestinal tract may support the occurrence of digestive symptoms and the possibility of fecal-to-oral transmission. Recent studies have shown positive fecal polymerase chain reaction (PCR) test results in patients with the infection who showed digestive symptoms. Therefore, we reviewed the related literature on the occurrence of digestive symptoms in patients with COVID-19 and present the usefulness and clinical application of the fecal PCR test for identifying the potential infection route and criteria for isolation.
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spelling doaj-art-e73d13a8cf9c44a6b6b32bcf1c578f2b2025-08-02T22:10:12ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312020-06-01202869010.7704/kjhugr.2020.0030628Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool TestSung Hoon Jung0Jung Hwan OhDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, KoreaCoronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a global pandemic and is now the most threatening public health issue. Patients with the infection present with high fever and pneumonia with respiratory symptoms, but some patients also develop digestive symptoms such as diarrhea, vomiting, and abdominal pain. This may be the basis for the transmission route of the new virus, not only for respiratory infection through droplets but also for fecal-to-oral transmission. In addition, the high expression level of angiotensin-converting enzyme 2 on the surface cells in the gastrointestinal tract may support the occurrence of digestive symptoms and the possibility of fecal-to-oral transmission. Recent studies have shown positive fecal polymerase chain reaction (PCR) test results in patients with the infection who showed digestive symptoms. Therefore, we reviewed the related literature on the occurrence of digestive symptoms in patients with COVID-19 and present the usefulness and clinical application of the fecal PCR test for identifying the potential infection route and criteria for isolation.http://www.helicojournal.org/upload/pdf/kjhugr-2020-0030.pdfabdominal paincoronaviruscovid-19diarrheavomiting
spellingShingle Sung Hoon Jung
Jung Hwan Oh
Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
abdominal pain
coronavirus
covid-19
diarrhea
vomiting
title Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
title_full Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
title_fullStr Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
title_full_unstemmed Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
title_short Gastrointestinal Symptoms in Patients with COVID-19 and Usefulness of Stool Test
title_sort gastrointestinal symptoms in patients with covid 19 and usefulness of stool test
topic abdominal pain
coronavirus
covid-19
diarrhea
vomiting
url http://www.helicojournal.org/upload/pdf/kjhugr-2020-0030.pdf
work_keys_str_mv AT sunghoonjung gastrointestinalsymptomsinpatientswithcovid19andusefulnessofstooltest
AT junghwanoh gastrointestinalsymptomsinpatientswithcovid19andusefulnessofstooltest