Refinement of the Reference Viral Database (RVDB) for improving bioinformatics analysis of virus detection by high-throughput sequencing (HTS)

ABSTRACT All biological products are required to demonstrate the absence of adventitious viruses (AVs), which may be inadvertently introduced at different steps involved in the manufacturing process. The currently recommended in vitro and in vivo virus detection assays have limitations for broad det...

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Bibliographic Details
Main Authors: Pei-Ju Chin, Jaysheel D. Bhavsar, Trent J. Bosma, Madolyn L. MacDonald, Shawn W. Polson, Arifa S. Khan
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00286-25
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