Reduced platelet aggregation in losartan-treated patients with arterial hypertension and metabolic syndrome

To assess the angiotensin II blocker effects on platelet (PL) aggregation in patients with arterial hypertension (AH) and metabolic syndrome (MS). In total, 35 patients received losartan for 16 weeks. Dynamics of plasma and PL lipid peroxidation, blood and PL antioxidant protection, and PL aggregati...

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Bibliographic Details
Main Authors: I. N. Medvedev, T. A. Kumova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2008-10-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1627
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Summary:To assess the angiotensin II blocker effects on platelet (PL) aggregation in patients with arterial hypertension (AH) and metabolic syndrome (MS). In total, 35 patients received losartan for 16 weeks. Dynamics of plasma and PL lipid peroxidation, blood and PL antioxidant protection, and PL aggregation activity was investigated and analyzed using Student t-test. Losartan therapy improved peroxidation and PL aggregation parameters in patients with AH and MS.
ISSN:1560-4071
2618-7620