The Outcome of Hospitalized Children with COVID-19 in a Referral Center in Yazd, Iran

Introduction:As there is limited research on COVID-19 in children, and reports have indicated low adverse clinical outcomes and mortality rates, our team conducted this study to investigate the clinical outcomes in hospitalized children with COVID-19. Materials and Methods: This historical cohort st...

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Main Authors: Zahra Nafei, Nasrin Behniafard, Mehran Karimi, Mehrdad Shakiba, Abdolhamid Jafari, farzad Ferdosian, Fakhrosadat Azarpeykan, Farimah Shamsi, Alireza Emarati
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-07-01
Series:Patient Safety and Quality Improvement Journal
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Online Access:https://psj.mums.ac.ir/article_23139_08ba34741a246a9e4bc7bde356001473.pdf
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Summary:Introduction:As there is limited research on COVID-19 in children, and reports have indicated low adverse clinical outcomes and mortality rates, our team conducted this study to investigate the clinical outcomes in hospitalized children with COVID-19. Materials and Methods: This historical cohort study included children aged 1 month to 18 years with COVID-19. They were admitted to a referral hospital in Yazd, Iran, over a year from February 2020. Demographic information such as age and sex, the length of hospitalization, and the reverse transcription-polymerase chain reaction (PCR) test results were recorded. We also evaluated Patients' outcomes, including admission to the pediatric intensive care unit (PICU), need for mechanical ventilation, and mortality. Results: Our study included 94 patients, of which 52.1% were female and 29.8% were under one year old. Children aged 1-59 months accounted for more than half of the sample (53.2%). The most common symptoms reported were fever (85.1%), respiratory problems (47.9%), and gastrointestinal symptoms (46.8%). The mean duration of hospital stay was 6.4±5.7 days. About 38.3% of cases required admission to the PICU, and 11.7% needed mechanical ventilation. 75% of deaths occurred in children with confirmed COVID-19 who had an underlying disease. Moreover, respiratory distress at the time of referral was significantly associated with admission to the intensive care unit (P=0.008), requiring mechanical ventilation (P=0.003), and mortality (P=0.02). Conclusion:Our findings suggest that children under one year old, patients with underlying diseases, and those experiencing respiratory distress at the time of referral are high-risk groups and require special attention in care and treatment.
ISSN:2345-4482
2345-4490