Two resected cases of benign adenomyoepithelioma
Abstract Background Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by the proliferation of ductal epithelial and myoepithelial cells with the heterogeneity. Although benign AME is relatively easy to differentiate from breast cancer by core needle biopsy (CNB) alone, a def...
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Japan Surgical Society
2023-12-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-023-01793-7 |
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| author | Yurika Fukudome Yoshika Nagata Yui Yamada Toshihiro Saeki Takahisa Fujikawa |
| author_facet | Yurika Fukudome Yoshika Nagata Yui Yamada Toshihiro Saeki Takahisa Fujikawa |
| author_sort | Yurika Fukudome |
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| description | Abstract Background Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by the proliferation of ductal epithelial and myoepithelial cells with the heterogeneity. Although benign AME is relatively easy to differentiate from breast cancer by core needle biopsy (CNB) alone, a definitive diagnosis is often difficult. The imaging findings of AME are also variable, and there are particularly few reports about radiological features, including contrast-enhanced magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) values in AME. Case presentation We present two cases of benign AME. Case 1 is a 30-year-old woman with a history of asthma. The cystic tumor shows smooth borders, and the intracystic solid component is irregular in shape and high vascularity. The pathological findings of the tumor were benign on CNB. The MRI scan showed a decreased ADC value. Case 2 is a 60-year-old woman with only a history of arrhythmia. The tumor shows a lobulated mass with cystic space and coarse calcifications. The pathological findings of the tumor were found to be benign by CNB. Dynamic MRI scan showed a fast washout pattern with a decreased ADC value. Both patients underwent excisional biopsy to confirm the diagnosis, and the pathological diagnosis was benign AME in both cases. Conclusions The AME of the breast has little specific imaging information, so it can be difficult to diagnose based on pathological findings of biopsy specimen. In our case, the ADC values were exceptionally low, contrary to previous reports. It is essential to carefully diagnose AME, considering the discrepancies in imaging findings observed in this case. |
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| institution | Matheson Library |
| issn | 2198-7793 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Japan Surgical Society |
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| series | Surgical Case Reports |
| spelling | doaj-art-e695b90c4b624f0686f8e444793d1a4f2025-08-02T22:06:43ZengJapan Surgical SocietySurgical Case Reports2198-77932023-12-01911810.1186/s40792-023-01793-7Two resected cases of benign adenomyoepitheliomaYurika Fukudome0Yoshika Nagata1Yui Yamada2Toshihiro Saeki3Takahisa Fujikawa4Department of Surgery, Kokura Memorial HospitalDepartment of Surgery, Kokura Memorial HospitalDepartment of Pathology, Kokura Memorial HospitalDepartment of Surgery, Kokura Memorial HospitalDepartment of Surgery, Kokura Memorial HospitalAbstract Background Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by the proliferation of ductal epithelial and myoepithelial cells with the heterogeneity. Although benign AME is relatively easy to differentiate from breast cancer by core needle biopsy (CNB) alone, a definitive diagnosis is often difficult. The imaging findings of AME are also variable, and there are particularly few reports about radiological features, including contrast-enhanced magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) values in AME. Case presentation We present two cases of benign AME. Case 1 is a 30-year-old woman with a history of asthma. The cystic tumor shows smooth borders, and the intracystic solid component is irregular in shape and high vascularity. The pathological findings of the tumor were benign on CNB. The MRI scan showed a decreased ADC value. Case 2 is a 60-year-old woman with only a history of arrhythmia. The tumor shows a lobulated mass with cystic space and coarse calcifications. The pathological findings of the tumor were found to be benign by CNB. Dynamic MRI scan showed a fast washout pattern with a decreased ADC value. Both patients underwent excisional biopsy to confirm the diagnosis, and the pathological diagnosis was benign AME in both cases. Conclusions The AME of the breast has little specific imaging information, so it can be difficult to diagnose based on pathological findings of biopsy specimen. In our case, the ADC values were exceptionally low, contrary to previous reports. It is essential to carefully diagnose AME, considering the discrepancies in imaging findings observed in this case.https://doi.org/10.1186/s40792-023-01793-7AdenomyoepitheliomaBreastApparent diffusion coefficientSurgical resection |
| spellingShingle | Yurika Fukudome Yoshika Nagata Yui Yamada Toshihiro Saeki Takahisa Fujikawa Two resected cases of benign adenomyoepithelioma Surgical Case Reports Adenomyoepithelioma Breast Apparent diffusion coefficient Surgical resection |
| title | Two resected cases of benign adenomyoepithelioma |
| title_full | Two resected cases of benign adenomyoepithelioma |
| title_fullStr | Two resected cases of benign adenomyoepithelioma |
| title_full_unstemmed | Two resected cases of benign adenomyoepithelioma |
| title_short | Two resected cases of benign adenomyoepithelioma |
| title_sort | two resected cases of benign adenomyoepithelioma |
| topic | Adenomyoepithelioma Breast Apparent diffusion coefficient Surgical resection |
| url | https://doi.org/10.1186/s40792-023-01793-7 |
| work_keys_str_mv | AT yurikafukudome tworesectedcasesofbenignadenomyoepithelioma AT yoshikanagata tworesectedcasesofbenignadenomyoepithelioma AT yuiyamada tworesectedcasesofbenignadenomyoepithelioma AT toshihirosaeki tworesectedcasesofbenignadenomyoepithelioma AT takahisafujikawa tworesectedcasesofbenignadenomyoepithelioma |