MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN
The article is devoted to gastroesophageal reflux disease (GERD) in children, which is of great medical and social significance. In spite of contemporary achievements in therapy, the diseaset is characterized by repeated relapses with complications. Hence it is very important to search for new patho...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2012-02-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/367 |
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| author | O. V. Syresina Y. A. Zhukova T. A. Vidmanova L. V. Korkotashvilly S. A. Kolesov O. A. Nefedova |
| author_facet | O. V. Syresina Y. A. Zhukova T. A. Vidmanova L. V. Korkotashvilly S. A. Kolesov O. A. Nefedova |
| author_sort | O. V. Syresina |
| collection | DOAJ |
| description | The article is devoted to gastroesophageal reflux disease (GERD) in children, which is of great medical and social significance. In spite of contemporary achievements in therapy, the diseaset is characterized by repeated relapses with complications. Hence it is very important to search for new pathogenetic schemes of esophagitis treatment. Therefore the efficacy of melatonine in complex therapy of gastroesophageal reflux disease was evaluated in 20 children. During the treatment a definitely positive dynamics was achieved: elimination of pain syndrome, absence of palpatory pain in epigastrics and pyloroduodenal region, decrease of the frequency of dyspeptic tendencies and also a significant decrease of registration of gastroesophageal reflux in control endoscopic investigation, improvement of acidforming function of the stomach as well as regulatory processes in digestion due to normalization of melatonine level were confirmed. It was scientifically proved that the use of the medicine in complex treatment of patients with GERD allows to increase efficacy of the studied therapy in 2,5 times. |
| format | Article |
| id | doaj-art-e624b6fe26604634b32b500b80f6d23a |
| institution | Matheson Library |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2012-02-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-e624b6fe26604634b32b500b80f6d23a2025-08-03T19:21:14ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892012-02-0191778010.15690/pf.v9i1.168367MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDRENO. V. Syresina0Y. A. Zhukova1T. A. Vidmanova2L. V. Korkotashvilly3S. A. Kolesov4O. A. Nefedova5The Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe Nizhniy Novgorod Scientific Research Institute of Childrens Gastroenterology, Nizhniy NovgorodThe article is devoted to gastroesophageal reflux disease (GERD) in children, which is of great medical and social significance. In spite of contemporary achievements in therapy, the diseaset is characterized by repeated relapses with complications. Hence it is very important to search for new pathogenetic schemes of esophagitis treatment. Therefore the efficacy of melatonine in complex therapy of gastroesophageal reflux disease was evaluated in 20 children. During the treatment a definitely positive dynamics was achieved: elimination of pain syndrome, absence of palpatory pain in epigastrics and pyloroduodenal region, decrease of the frequency of dyspeptic tendencies and also a significant decrease of registration of gastroesophageal reflux in control endoscopic investigation, improvement of acidforming function of the stomach as well as regulatory processes in digestion due to normalization of melatonine level were confirmed. It was scientifically proved that the use of the medicine in complex treatment of patients with GERD allows to increase efficacy of the studied therapy in 2,5 times.https://www.pedpharma.ru/jour/article/view/367gastroesophageal reflux diseasemelatonintreatmentchildren |
| spellingShingle | O. V. Syresina Y. A. Zhukova T. A. Vidmanova L. V. Korkotashvilly S. A. Kolesov O. A. Nefedova MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN Педиатрическая фармакология gastroesophageal reflux disease melatonin treatment children |
| title | MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN |
| title_full | MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN |
| title_fullStr | MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN |
| title_full_unstemmed | MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN |
| title_short | MELATONIN IN COMPLEX TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE IN CHILDREN |
| title_sort | melatonin in complex treatment of gastroesophageal reflux disease in children |
| topic | gastroesophageal reflux disease melatonin treatment children |
| url | https://www.pedpharma.ru/jour/article/view/367 |
| work_keys_str_mv | AT ovsyresina melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren AT yazhukova melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren AT tavidmanova melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren AT lvkorkotashvilly melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren AT sakolesov melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren AT oanefedova melatoninincomplextreatmentofgastroesophagealrefluxdiseaseinchildren |