Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

QR Code

Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

PurposeThis research aims to develop prognostic nomograms to predict tumor recurrence and recurrence-free survival (RFS) in individuals with initially unresectable hepatocellular carcinoma (uHCC) who were later subjected to conversion hepatectomy following lenvatinib, PD-1 inhibitors, and interventi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Cheng Xu, Zhihong Tang, Meng Wei, Danxi Liu, Qingqing Pang, Baishan Huang, Xinglin Mo, Feixiang Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	hepatocellular carcinoma hepatectomy recurrence recurrence-free survival nomogram model
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1602327/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Classification of microvascular invasion of hepatocellular carcinoma: Different standards, common goals: Letter to the editor on “Classification of microvascular invasion of hepatocellular carcinoma: Correlation with prognosis and magnetic resonance imaging”
by: Wei Chen, et al.
Published: (2025-07-01)

Conversion hepatectomy for advanced hepatocellular carcinoma after right portal vein transection and lenvatinib therapy
by: Yuki Ohya, et al.
Published: (2020-12-01)

Adjuvant Lenvatinib for High-Risk CNLC IIb/IIIa Hepatocellular Carcinoma After Curative Hepatectomy: A Prospective Exploratory Study
by: Sun HC, et al.
Published: (2025-05-01)

Hepatic Arterial Infusion Chemotherapy Combined Apatinib/Camrelizumab for Recurrent Hepatocellular Carcinoma After Hepatectomy
by: Zheng X, et al.
Published: (2025-06-01)

Nomogram based on tumor burden score for prediction of prognosis of patients with hepatocellular carcinoma before hepatectomy
by: Qianru Xiao, et al.
Published: (2025-07-01)

Aspartate aminotransferase-to-platelet ratio index for predicting late recurrence of hepatocellular carcinoma after radiofrequency ablation
by: Xinyuan Zhang, et al.
Published: (2022-12-01)

Survival Benefit of Adjuvant Treatment with Huaier Granules Plus Lenvatinib in Hepatocellular Carcinoma Patients with Tumors Greater Than 5 cm After Radical Hepatectomy
by: Liu C, et al.
Published: (2025-07-01)

Ablative Volume of Radiofrequency Ablation Related to Intrahepatic Recurrence-Free Survival of Hepatocellular Carcinoma
by: Nakarin Inmutto, et al.
Published: (2021-07-01)

Characteristics recurrence pattern of cholangiolocellular carcinoma as intrahepatic bile duct tumor growth following curative resection: a case report
by: Keishi Hakoda, et al.
Published: (2019-09-01)

Post-hepatectomy tolvaptan-induced hypernatremia in a hepatocellular carcinoma patient with cirrhosis: a case report
by: Hiroya Iida, et al.
Published: (2020-03-01)

Laparoscopic hepatectomy for hepatocellular carcinoma in a patient with congenital factor V deficiency: a case report
by: Takaomi Seki, et al.
Published: (2022-10-01)

Comparison of Computed Tomography and Ultrasound-Guided Radiofrequency Ablation for Recurrent Subdiaphragmatic Hepatocellular Carcinoma After Resection
by: Liu HY, et al.
Published: (2025-06-01)

Postoperative recurrence with right cervical lymph node metastasis in hepatocellular carcinoma: a case report
by: Kiyonori Tanoue, et al.
Published: (2021-12-01)

Pan-Immune-Inflammation Value as a Prognostic Biomarker for Hepatocellular Carcinoma Patients Undergoing Hepatectomy
by: Fu H, et al.
Published: (2025-05-01)

A scoring model based on MRI features for predicting early recurrence after surgical resection of hepatocellular carcinoma
by: Yi-Jing Wang, et al.
Published: (2025-08-01)

Comparison of Long-Term Outcomes Between Repeated Hepatic Resection and Radiofrequency Ablation in Patients with Small Recurrent Hepatocellular Carcinoma After Initial Curative Resection: A Propensity Score Matched Study
by: Hsiao CY, et al.
Published: (2025-07-01)

Successful two-stage transplant hepatectomy using the ALPPS procedure for advanced hepatocellular cancer
by: D. A. Granov, et al.
Published: (2024-01-01)

Central hepatectomy for hepatocellular carcinoma in a patient with anti-Gerbich antibody
by: Teruo Komokata, et al.
Published: (2020-06-01)

Early Recurrence of Hepatocellular Carcinoma in Patients without Microscopic Vascular Invasion: Clinicopathological Characteristics and Risk Factors
by: Ngo HTT, et al.
Published: (2025-06-01)

Prognostic utility of the global leadership initiative on malnutrition criteria in predicting outcomes after hepatectomy for hepatocellular carcinoma: a multicenter, retrospective study
by: Yaohao Liang, et al.
Published: (2025-06-01)

Integrating CEUS Imaging Features and LI-RADS Classification for Postoperative Early Recurrence Prediction in Solitary Hepatocellular Carcinoma: A Machine Learning-Based Prognostic Approach
by: Liang L, et al.
Published: (2025-07-01)

Hyper-Relapse Disease is a Special Pattern of Relapse of Hepatocellular Carcinoma After Curative Hepatectomy: A Retrospective Cohort Study
by: Yang ZL, et al.
Published: (2025-07-01)

Efficacy Analysis of TACE Combined with Lenvatinib and PD-1 Inhibitors in the Treatment of Hepatitis B Virus-Related Unresectable Hepatocellular Carcinoma
by: Yu J, et al.
Published: (2025-07-01)

Prognostic Value of Gd-BOPTA Enhanced MRI in Solitary Resected Hepatocellular Carcinoma Without Microvascular Invasion
by: Zhang J, et al.
Published: (2025-07-01)

Long-term results of liver transplantation for hepatocellular carcinoma
by: M. Sh. Khubutia, et al.
Published: (2018-08-01)

Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice
by: V. V. Petkau, et al.
Published: (2022-12-01)

Unclassified hepatocellular adenoma with beta-catenin mutation: a case report
by: Ryo Muranushi, et al.
Published: (2021-02-01)

TREATMENT FOR RECURRENT GLIOBLASTOMA: ARE THERE SUCCESSES?
by: G. I. Kobyakov, et al.
Published: (2015-04-01)

Predictors of local recurrence of renal cell cancer. Our experience
by: M. Y. Gaas, et al.
Published: (2022-09-01)

New prognostic model for liver transplantation outcomes in hepatocellular carcinoma
by: S. E. Voskanyan, et al.
Published: (2024-09-01)

EXPERIENCE OF SURGICAL TREATMENT AT RECURRENT GASTRIC CANCER
by: A. V. Chayka, et al.
Published: (2016-02-01)

“White spots” in the diagnostic search for the causes of recurrent miscarriage
by: E. Yu. Lebedenko, et al.
Published: (2024-03-01)

Recurrence of cardiac myxoma. Clinical and morphological aspects
by: I. M. Iljinsky, et al.
Published: (2018-01-01)

Importance to Promote Awareness in Patients with Recurrent Cystitis
by: Sun-tae Ahn, et al.
Published: (2022-12-01)

Importance of immunotherapy in the treatment of recurrent cystitis
by: Kh. S. Ibishev, et al.
Published: (2021-03-01)

A Novel Nomogram for Prediction of Survival in Patients with Small Isolated Hepatocellular Carcinoma: A Population-Based and Externally Validated Study
by: Ziqiang Li, et al.
Published: (2025-12-01)

Emergency open drainage of massive hemoperitoneum and early stage left hepatectomy for abdominal compartment syndrome due to hepatocellular carcinoma rupture: a case report
by: Makoto Kurimoto, et al.
Published: (2022-06-01)

Postoperative hepatitis B virus reactivation and its impact on survival in HBV-related hepatocellular carcinoma patients undergoing conversion therapy with interventional therapy combined with tyrosine kinase inhibitors and immune checkpoint inhibitors
by: Shaowei Xu, et al.
Published: (2025-07-01)

Prognostic Value of the SII-PNI Score in Unresectable HCC Treated with Transcatheter Arterial Chemoembolization Combined with Lenvatinib and PD-1 Inhibitors
by: Wei SM, et al.
Published: (2025-06-01)

Recurrency on the Space of Hilbert-Schmidt Operators
by: Mansooreh Moosapoor
Published: (2024-05-01)