Autophagy and Alzheimer’s Disease: Mechanisms and Impact Beyond the Brain

Autophagy and Alzheimer’s Disease: Mechanisms and Impact Beyond the Brain

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by neuronal loss, cognitive decline, and pathological hallmarks such as amyloid-beta (Aβ) plaques and tau neurofibrillary tangles. Recent evidence highlights autophagy as a pivotal mechanism in cellular homeostasis, mediatin...

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Bibliographic Details
Main Authors: Zaw Myo Hein, Thirupathirao Vishnumukkala, Barani Karikalan, Aisyah Alkatiri, Farida Hussan, Saravanan Jagadeesan, Mohd Amir Kamaruzzaman, Muhammad Danial Che Ramli, Che Mohd Nasril Che Mohd Nassir, Prarthana Kalerammana Gopalakrishna
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
Alzheimer’s disease
autophagy
amyloid-beta clearance
tau pathology
neurodegeneration
Online Access:https://www.mdpi.com/2073-4409/14/12/911
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