SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION
In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation. Also, in the article were shown the physical and chemical characteristics of API, matrix and excipie...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/160 |
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| _version_ | 1839586811229241344 |
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| author | N. B. Diomina M. N. Anurova |
| author_facet | N. B. Diomina M. N. Anurova |
| author_sort | N. B. Diomina |
| collection | DOAJ |
| description | In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation. Also, in the article were shown the physical and chemical characteristics of API, matrix and excipients (surface-active agents, prolongation agents, cyclodextrines, etc.). Was presented information about mucoadhesive suppositories, suppositories with different types of release methods (immediate intensive or prolonged) and poloxamer-based thermo-reversible liquid suppositories (characteristics, pharmaceutical, technological and biopharmaceutical parameters of quality). |
| format | Article |
| id | doaj-art-e4acdc6ef5b54b89a6c2d77dae85a41f |
| institution | Matheson Library |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-e4acdc6ef5b54b89a6c2d77dae85a41f2025-08-03T19:23:53ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01049297160SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATIONN. B. Diomina0M. N. Anurova1I.M.Sechenov First Moskow State Medical UniversityI.M.Sechenov First Moskow State Medical UniversityIn this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation. Also, in the article were shown the physical and chemical characteristics of API, matrix and excipients (surface-active agents, prolongation agents, cyclodextrines, etc.). Was presented information about mucoadhesive suppositories, suppositories with different types of release methods (immediate intensive or prolonged) and poloxamer-based thermo-reversible liquid suppositories (characteristics, pharmaceutical, technological and biopharmaceutical parameters of quality).https://www.pharmjournal.ru/jour/article/view/160suppositoriesmucoadhesivethermo-reversible liquid suppositoriespoloxamer |
| spellingShingle | N. B. Diomina M. N. Anurova SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION Разработка и регистрация лекарственных средств suppositories mucoadhesive thermo-reversible liquid suppositories poloxamer |
| title | SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION |
| title_full | SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION |
| title_fullStr | SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION |
| title_full_unstemmed | SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION |
| title_short | SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION |
| title_sort | suppositories aspects of dosage form modernization |
| topic | suppositories mucoadhesive thermo-reversible liquid suppositories poloxamer |
| url | https://www.pharmjournal.ru/jour/article/view/160 |
| work_keys_str_mv | AT nbdiomina suppositoriesaspectsofdosageformmodernization AT mnanurova suppositoriesaspectsofdosageformmodernization |