SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION
In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation. Also, in the article were shown the physical and chemical characteristics of API, matrix and excipie...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
|
| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/160 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation. Also, in the article were shown the physical and chemical characteristics of API, matrix and excipients (surface-active agents, prolongation agents, cyclodextrines, etc.). Was presented information about mucoadhesive suppositories, suppositories with different types of release methods (immediate intensive or prolonged) and poloxamer-based thermo-reversible liquid suppositories (characteristics, pharmaceutical, technological and biopharmaceutical parameters of quality). |
|---|---|
| ISSN: | 2305-2066 2658-5049 |