Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF

He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml.

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Bibliographic Details
Main Authors: O. G. Gribakina, R. V. Shevchenko, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, S. S. Boyko, V. P. Zherdev
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2019-02-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/93
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