Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF
He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml.
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Main Authors: | O. G. Gribakina, R. V. Shevchenko, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, S. S. Boyko, V. P. Zherdev |
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Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2019-02-01
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Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/93 |
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