Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF
He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC “Publisher OKI”
2019-02-01
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| Series: | Фармакокинетика и Фармакодинамика |
| Subjects: | |
| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/93 |
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| Summary: | He technique of quantitative determination of a new compound GIZH-298 in the rat blood plasma was developed and validated. Analysis was performed by HPLC-UV. The method was linear in the range of 100-5000 ng/ml. Recovery of GIZH-298 was 86,88 %. Limit of detection was 100 ng/ml. |
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| ISSN: | 2587-7836 2686-8830 |