Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk
Aim. To study lipid-lowering therapy in patients with high and very high risk of cardiovascular events (CVEs) at the outpatient and inpatient care stages in Irkutsk.Material and methods. We analyzed 260 discharge summaries of patients with hypertension of high and very high risk of CVEs for the seco...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2021-11-01
|
| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3073 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839577863129399296 |
|---|---|
| author | O. A. Ivanova S. G. Kuklin S. S. Sizova T. A. Novoselova L. R. Gaifullina |
| author_facet | O. A. Ivanova S. G. Kuklin S. S. Sizova T. A. Novoselova L. R. Gaifullina |
| author_sort | O. A. Ivanova |
| collection | DOAJ |
| description | Aim. To study lipid-lowering therapy in patients with high and very high risk of cardiovascular events (CVEs) at the outpatient and inpatient care stages in Irkutsk.Material and methods. We analyzed 260 discharge summaries of patients with hypertension of high and very high risk of CVEs for the second half of 2019: 145 — from a hospital; 115 — from outpatient records. Patient adherence to statin therapy, achievement of target lowdensity lipoprotein cholesterol (LDL-C) levels in each patient subgroup was assessed.Results. The proportion of patients who reached the recommended LDL-C levels in accordance with the 2017 guidelines tends to increase in comparison with prior data. High adherence to lipid-lowering therapy was accompanied by an increase in the proportion of patients reaching the recommended LDL-C levels. In most cases, regardless of cardiovascular risk, low-dose statin therapy were used. A detailed analysis of adherence to statin therapy using questionnaires revealed that more than half of patients in high-risk categories (64%) did not comply with lipid-lowering therapy.Conclusion. Favorable trends were revealed in relation to an increase in the proportion of high-risk patients reaching target LDL-C levels. Adherence to statin therapy remains low. Previously established problems in managing such patients remains: stereotyped lipid-lowering therapy prescriptions without taking into account cardiovascular risk, the use of low-dose therapy, and the frequent prescription of statins with a lower lipid-lowering effect. Inpatients use higher statin doses than outpatients. |
| format | Article |
| id | doaj-art-e3f16f01ff5d44b5a798b65e670b1df5 |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2021-11-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-e3f16f01ff5d44b5a798b65e670b1df52025-08-04T12:50:27Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-11-0120710.15829/1728-8800-2021-30732393Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in IrkutskO. A. Ivanova0S. G. Kuklin1S. S. Sizova2T. A. Novoselova3L. R. Gaifullina4Irkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education — branch of the Russian Medical Academy of Continuing Professional EducationAim. To study lipid-lowering therapy in patients with high and very high risk of cardiovascular events (CVEs) at the outpatient and inpatient care stages in Irkutsk.Material and methods. We analyzed 260 discharge summaries of patients with hypertension of high and very high risk of CVEs for the second half of 2019: 145 — from a hospital; 115 — from outpatient records. Patient adherence to statin therapy, achievement of target lowdensity lipoprotein cholesterol (LDL-C) levels in each patient subgroup was assessed.Results. The proportion of patients who reached the recommended LDL-C levels in accordance with the 2017 guidelines tends to increase in comparison with prior data. High adherence to lipid-lowering therapy was accompanied by an increase in the proportion of patients reaching the recommended LDL-C levels. In most cases, regardless of cardiovascular risk, low-dose statin therapy were used. A detailed analysis of adherence to statin therapy using questionnaires revealed that more than half of patients in high-risk categories (64%) did not comply with lipid-lowering therapy.Conclusion. Favorable trends were revealed in relation to an increase in the proportion of high-risk patients reaching target LDL-C levels. Adherence to statin therapy remains low. Previously established problems in managing such patients remains: stereotyped lipid-lowering therapy prescriptions without taking into account cardiovascular risk, the use of low-dose therapy, and the frequent prescription of statins with a lower lipid-lowering effect. Inpatients use higher statin doses than outpatients.https://cardiovascular.elpub.ru/jour/article/view/3073lipid-lowering therapystatinshigh and very high riskcardiovascular eventsmorisky-green test |
| spellingShingle | O. A. Ivanova S. G. Kuklin S. S. Sizova T. A. Novoselova L. R. Gaifullina Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk Кардиоваскулярная терапия и профилактика lipid-lowering therapy statins high and very high risk cardiovascular events morisky-green test |
| title | Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk |
| title_full | Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk |
| title_fullStr | Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk |
| title_full_unstemmed | Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk |
| title_short | Comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in Irkutsk |
| title_sort | comparative effectiveness of statin therapy in patients with hypertension of high and very high cardiovascular risk in actual clinical practice in irkutsk |
| topic | lipid-lowering therapy statins high and very high risk cardiovascular events morisky-green test |
| url | https://cardiovascular.elpub.ru/jour/article/view/3073 |
| work_keys_str_mv | AT oaivanova comparativeeffectivenessofstatintherapyinpatientswithhypertensionofhighandveryhighcardiovascularriskinactualclinicalpracticeinirkutsk AT sgkuklin comparativeeffectivenessofstatintherapyinpatientswithhypertensionofhighandveryhighcardiovascularriskinactualclinicalpracticeinirkutsk AT sssizova comparativeeffectivenessofstatintherapyinpatientswithhypertensionofhighandveryhighcardiovascularriskinactualclinicalpracticeinirkutsk AT tanovoselova comparativeeffectivenessofstatintherapyinpatientswithhypertensionofhighandveryhighcardiovascularriskinactualclinicalpracticeinirkutsk AT lrgaifullina comparativeeffectivenessofstatintherapyinpatientswithhypertensionofhighandveryhighcardiovascularriskinactualclinicalpracticeinirkutsk |