REACTIVE PLASMACYTOSIS AT THE ONSET OF ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA. CASE REPORT

Angioimmunoblastic T-cell lymphoma is a rare T-cell lymphoproliferative disease with generalized lymphadenopathy, hepatosplenomegaly, intoxication and polyclonal hypergammaglobulinemia. The persistence of plasma cells in peripheral blood can be a manifestation of both tumor and reactive processes. I...

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Bibliographic Details
Main Authors: N. G. Chernova, M. N. Sinitsyna, A. M. Kovrigina, Y. V. Sidorova, I. V. Galtseva, S. A. Mar’ina, V. N. Dvirnyk, E. E. Zvonkov
Format: Article
Language:Russian
Published: ABV-press 2018-02-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/264
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Summary:Angioimmunoblastic T-cell lymphoma is a rare T-cell lymphoproliferative disease with generalized lymphadenopathy, hepatosplenomegaly, intoxication and polyclonal hypergammaglobulinemia. The persistence of plasma cells in peripheral blood can be a manifestation of both tumor and reactive processes. In our article, we described the case of angioimmunoblastic T-cell lymphoma with an increase in the number of peripheral blood plasma cells to 28 %, and in bone marrow to 9 %. The complex diagnostics, including plasma cells immunophenotyping, morphology of the lymph node biopsy and bone marrow samples, made it possible to verify the diagnosis of angioimmunoblastic T-cell lymphoma with polyclonal plasmacytosis.
ISSN:1818-8346
2413-4023