Anacyphrethines A and B as potent analgesics: Multiple ion channel inhibitors with an unprecedented chemical architecture
Multi-target analgesics with minimal side effects and high efficacy are a key research focus in addressing the global pain crisis. Using a molecular networking approach, five pairs of potent analgesic alkaloid enantiomers were isolated from the roots of Anacyclus pyrethrum (A. pyrethrum). Their stru...
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Main Authors: | Hui Chen, Hanqi Zhang, Chao Niu, Bianlin Wang, Biao Gao, Zhijun Liu, Guangmin Yao, Haji Akber Aisa |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-07-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383525002990 |
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