Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study
Background: Glycated hemoglobin A1c (HbA1c) level is related to increased cardiovascular diseases (CVDs) and death, even in non-diabetic subjects. Although in ST-elevation myocardial infarction (STEMI) cases, the association between HbA1c and coronary artery disease (CAD) remains unclear. Methods:...
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Babol University of Medical Sciences
2025-06-01
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| Series: | Caspian Journal of Internal Medicine |
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| Online Access: | http://caspjim.com/article-1-4249-en.pdf |
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| author | Majid Saraei koushki Razieh parizad Ali Abdollahzadeh Ahmad Separham |
| author_facet | Majid Saraei koushki Razieh parizad Ali Abdollahzadeh Ahmad Separham |
| author_sort | Majid Saraei koushki |
| collection | DOAJ |
| description | Background: Glycated hemoglobin A1c (HbA1c) level is related to increased cardiovascular diseases (CVDs) and death, even in non-diabetic subjects. Although in ST-elevation myocardial infarction (STEMI) cases, the association between HbA1c and coronary artery disease (CAD) remains unclear.
Methods: This cross-sectional study was conducted on 167 non-diabetic STEMI patients undergoing primary percutaneous coronary intervention (PCI). The SYNTAX score was utilized to evaluate CAD severity. Cases were categorized into three groups based on the HbA1c levels: <5%, 5.1-5.9%, and 6-6.5%.
Results: SYNTAX scores significantly increased in the cases with 6 to 6.5 HbA1c levels compared to the other group (28.9±9.5 vs 21.2±5.2 vs 13.7±4.5, P=0.000). Additionally, death was more elevated in this group (4% vs 0% vs 0%, P=0.006).
Conclusion: Higher HbA1c levels are strongly associated with coronary atherosclerosis in non-diabetic patients that present with non-diabetic STEMI. Consequently, in non-diabetic STEMI patients, HbA1c may be able to predict the severity of CAD. |
| format | Article |
| id | doaj-art-e0fe2fadb95e48faa3eaa254cac82dda |
| institution | Matheson Library |
| issn | 2008-6164 2008-6172 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj-art-e0fe2fadb95e48faa3eaa254cac82dda2025-07-19T07:07:27ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722025-06-01163519524Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional studyMajid Saraei koushki0Razieh parizad1Ali Abdollahzadeh2Ahmad Separham3 Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Background: Glycated hemoglobin A1c (HbA1c) level is related to increased cardiovascular diseases (CVDs) and death, even in non-diabetic subjects. Although in ST-elevation myocardial infarction (STEMI) cases, the association between HbA1c and coronary artery disease (CAD) remains unclear. Methods: This cross-sectional study was conducted on 167 non-diabetic STEMI patients undergoing primary percutaneous coronary intervention (PCI). The SYNTAX score was utilized to evaluate CAD severity. Cases were categorized into three groups based on the HbA1c levels: <5%, 5.1-5.9%, and 6-6.5%. Results: SYNTAX scores significantly increased in the cases with 6 to 6.5 HbA1c levels compared to the other group (28.9±9.5 vs 21.2±5.2 vs 13.7±4.5, P=0.000). Additionally, death was more elevated in this group (4% vs 0% vs 0%, P=0.006). Conclusion: Higher HbA1c levels are strongly associated with coronary atherosclerosis in non-diabetic patients that present with non-diabetic STEMI. Consequently, in non-diabetic STEMI patients, HbA1c may be able to predict the severity of CAD.http://caspjim.com/article-1-4249-en.pdfcoronary syntax scorehba1cnon-diabeticmyocardial infarction |
| spellingShingle | Majid Saraei koushki Razieh parizad Ali Abdollahzadeh Ahmad Separham Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study Caspian Journal of Internal Medicine coronary syntax score hba1c non-diabetic myocardial infarction |
| title | Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study |
| title_full | Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study |
| title_fullStr | Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study |
| title_full_unstemmed | Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study |
| title_short | Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study |
| title_sort | impact of hba1c levels on coronary syntax score in non diabetic patients with st elevation myocardial infarction undergoing primary angioplasty a cross sectional study |
| topic | coronary syntax score hba1c non-diabetic myocardial infarction |
| url | http://caspjim.com/article-1-4249-en.pdf |
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