Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion
Abstract Obesity is associated with skeletal deterioration and increased fracture risk, but the underlying mechanism is unclear. Herein, it is shown that obese gut microbiota promotes skeletal deterioration by inducing bone marrow macrophages (BMMs) senescence and grancalcin (GCA) secretion. Obese m...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Wiley
2025-07-01
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| 叢編: | Advanced Science |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1002/advs.202502634 |
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