Synthesis and Characterization of Some New Benzimidazole Derivatives

In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesi...

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Главный автор: Baghdad Science Journal
Формат: Статья
Язык:английский
Опубликовано: University of Baghdad, College of Science for Women 2016-03-01
Серии:مجلة بغداد للعلوم
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Online-ссылка:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra.
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publishDate 2016-03-01
publisher University of Baghdad, College of Science for Women
record_format Article
series مجلة بغداد للعلوم
spelling doaj-art-e07027e17f804eee8385ff4ada3f9ff32025-08-02T21:31:18ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862016-03-0113110.21123/bsj.13.1.82-88Synthesis and Characterization of Some New Benzimidazole DerivativesBaghdad Science JournalIn this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145"Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
spellingShingle Baghdad Science Journal
Synthesis and Characterization of Some New Benzimidazole Derivatives
مجلة بغداد للعلوم
"Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
title Synthesis and Characterization of Some New Benzimidazole Derivatives
title_full Synthesis and Characterization of Some New Benzimidazole Derivatives
title_fullStr Synthesis and Characterization of Some New Benzimidazole Derivatives
title_full_unstemmed Synthesis and Characterization of Some New Benzimidazole Derivatives
title_short Synthesis and Characterization of Some New Benzimidazole Derivatives
title_sort synthesis and characterization of some new benzimidazole derivatives
topic "Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145
work_keys_str_mv AT baghdadsciencejournal synthesisandcharacterizationofsomenewbenzimidazolederivatives