Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives
Traditionally, radiotherapy in metastatic renal cell carcinoma (RCC) was applied for the palliation of symptoms and the control of critical sites such as bone lesions and brain metastases. However, technological advances in radiotherapy (RT) planning and delivery made it possible to precisely delive...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-07-01
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| Series: | Technology in Cancer Research & Treatment |
| Online Access: | https://doi.org/10.1177/15330338251357344 |
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| author | Sander Vandaele MD Maarten Albersen MD, PhD Benoit Beuselinck MD, PhD Karolien Goffin MD, PhD Vincent Vandecaveye MD, PhD Henri Vandermeulen MD Charlien Berghen MD, PhD |
| author_facet | Sander Vandaele MD Maarten Albersen MD, PhD Benoit Beuselinck MD, PhD Karolien Goffin MD, PhD Vincent Vandecaveye MD, PhD Henri Vandermeulen MD Charlien Berghen MD, PhD |
| author_sort | Sander Vandaele MD |
| collection | DOAJ |
| description | Traditionally, radiotherapy in metastatic renal cell carcinoma (RCC) was applied for the palliation of symptoms and the control of critical sites such as bone lesions and brain metastases. However, technological advances in radiotherapy (RT) planning and delivery made it possible to precisely deliver high dose radiotherapy at a confined target volume. One such approach is stereotactic body radiotherapy (SBRT). In patients presenting with limited metastatic burden, known as oligometastatic RCC (omRCC), SBRT can be of interest to maintain local control, in order to defer the onset of either a first or a subsequent line of systemic treatment. In this narrative review, we summarize the prospective and retrospective evidence on SBRT as a treatment option for omRCC, and give insight into the future perspectives. |
| format | Article |
| id | doaj-art-e03b2bcb9335422f8a9929c87c5c07e7 |
| institution | Matheson Library |
| issn | 1533-0338 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Technology in Cancer Research & Treatment |
| spelling | doaj-art-e03b2bcb9335422f8a9929c87c5c07e72025-07-17T09:03:38ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382025-07-012410.1177/15330338251357344Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future PerspectivesSander Vandaele MD0Maarten Albersen MD, PhD1Benoit Beuselinck MD, PhD2Karolien Goffin MD, PhD3Vincent Vandecaveye MD, PhD4Henri Vandermeulen MD5Charlien Berghen MD, PhD6 Catholic University of Leuven, Leuven, Belgium Department of Urology, University Hospitals Leuven, Leuven, Belgium Department of Medical Oncology, University Hospitals Leuven, Leuven, Belgium Department of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium Department of Radiology, University Hospitals Leuven, Leuven, Belgium Department of Radiology, University Hospitals Leuven, Leuven, Belgium Catholic University of Leuven, Leuven, BelgiumTraditionally, radiotherapy in metastatic renal cell carcinoma (RCC) was applied for the palliation of symptoms and the control of critical sites such as bone lesions and brain metastases. However, technological advances in radiotherapy (RT) planning and delivery made it possible to precisely deliver high dose radiotherapy at a confined target volume. One such approach is stereotactic body radiotherapy (SBRT). In patients presenting with limited metastatic burden, known as oligometastatic RCC (omRCC), SBRT can be of interest to maintain local control, in order to defer the onset of either a first or a subsequent line of systemic treatment. In this narrative review, we summarize the prospective and retrospective evidence on SBRT as a treatment option for omRCC, and give insight into the future perspectives.https://doi.org/10.1177/15330338251357344 |
| spellingShingle | Sander Vandaele MD Maarten Albersen MD, PhD Benoit Beuselinck MD, PhD Karolien Goffin MD, PhD Vincent Vandecaveye MD, PhD Henri Vandermeulen MD Charlien Berghen MD, PhD Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives Technology in Cancer Research & Treatment |
| title | Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives |
| title_full | Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives |
| title_fullStr | Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives |
| title_full_unstemmed | Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives |
| title_short | Stereotactic Body Radiotherapy for Extracranial Oligometastatic Renal Cell Carcinoma: State of the Art and Future Perspectives |
| title_sort | stereotactic body radiotherapy for extracranial oligometastatic renal cell carcinoma state of the art and future perspectives |
| url | https://doi.org/10.1177/15330338251357344 |
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