The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism

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The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism

BackgroundBreast cancer is characterized as highly heterogenous and is a representative model to understand how molecular features of tumor biology determine therapeutic strategy. LINC01133 exhibits opposing expressing patterns across different breast cancer subtypes, yet its roles and mechanisms in...

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Bibliografiset tiedot
Päätekijät:	Mai-dong Li, Ben-jie Shan, Lei Wang, Shuang Gao, Li Hao, Hai-yang Yu, Yue-yin Pan
Aineistotyyppi:	Artikkeli
Kieli:	englanti
Julkaistu:	Frontiers Media S.A. 2025-06-01
Sarja:	Frontiers in Oncology
Aiheet:	LINC01133 IGF2BP2 m6A METTL3 heterogenous
Linkit:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1608574/full
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!

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