Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury
A penetrating corneoscleral injury case with the development of bilateral phacoanaphylactic inflammation of a sympathetic ophthalmia kind in a 59-year-old woman is described. The case reveals a difference between bilateral phacoanaphylactic inflammation and classical sympathetic ophthalmia. Unlike t...
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Real Time Ltd
2021-03-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/587 |
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| author | N. L. Leparskaya I. P. Khoroshilova-Maslova A. S. Voronin |
| author_facet | N. L. Leparskaya I. P. Khoroshilova-Maslova A. S. Voronin |
| author_sort | N. L. Leparskaya |
| collection | DOAJ |
| description | A penetrating corneoscleral injury case with the development of bilateral phacoanaphylactic inflammation of a sympathetic ophthalmia kind in a 59-year-old woman is described. The case reveals a difference between bilateral phacoanaphylactic inflammation and classical sympathetic ophthalmia. Unlike the latter, the clinical case showed on the “healthy” eye a sluggish inflammation of anterior uveitis type with a slowly progressing lens opacity, for which local and systemic corticosteroid therapy proved insufficiently effective. The morphological picture showed that the inflammation was located in the anterior part of the eye around the damaged lens with the formation of a macrophage-neutrophil abscess, which is typical for phacoanaphylactic inflammation, and the absence of granulomatous inflammation in the ciliary body, where plasmacellular infiltration prevailed.Conclusions. Phacoanaphylactic inflammation and sympathetic inflammation are autoimmune in their nature having different autoantigens. In phacoanaphylactic inflammation, autoantigen is the lens protein, while in sympathetic inflammation it is the uveoretinal antigen. The only method of treating phacoanaphylactic inflammation is to remove the cataract-altered lens. Our patient underwent phacoemulsification in her single eye, after which the symptoms of uveitis with hypertension disappeared completely and her vision was restored. |
| format | Article |
| id | doaj-art-e00e4f3e7eb644d1bb46ed524acad41c |
| institution | Matheson Library |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2021-03-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-e00e4f3e7eb644d1bb46ed524acad41c2025-08-03T19:22:33ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602021-03-01141747910.21516/2072-0076-2021-14-1-74-79339Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injuryN. L. Leparskaya0I. P. Khoroshilova-Maslova1A. S. Voronin2Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesA penetrating corneoscleral injury case with the development of bilateral phacoanaphylactic inflammation of a sympathetic ophthalmia kind in a 59-year-old woman is described. The case reveals a difference between bilateral phacoanaphylactic inflammation and classical sympathetic ophthalmia. Unlike the latter, the clinical case showed on the “healthy” eye a sluggish inflammation of anterior uveitis type with a slowly progressing lens opacity, for which local and systemic corticosteroid therapy proved insufficiently effective. The morphological picture showed that the inflammation was located in the anterior part of the eye around the damaged lens with the formation of a macrophage-neutrophil abscess, which is typical for phacoanaphylactic inflammation, and the absence of granulomatous inflammation in the ciliary body, where plasmacellular infiltration prevailed.Conclusions. Phacoanaphylactic inflammation and sympathetic inflammation are autoimmune in their nature having different autoantigens. In phacoanaphylactic inflammation, autoantigen is the lens protein, while in sympathetic inflammation it is the uveoretinal antigen. The only method of treating phacoanaphylactic inflammation is to remove the cataract-altered lens. Our patient underwent phacoemulsification in her single eye, after which the symptoms of uveitis with hypertension disappeared completely and her vision was restored.https://roj.igb.ru/jour/article/view/587sympathetic ophthalmiaphacoanaphylactic endophthalmitisopen globe injury |
| spellingShingle | N. L. Leparskaya I. P. Khoroshilova-Maslova A. S. Voronin Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury Российский офтальмологический журнал sympathetic ophthalmia phacoanaphylactic endophthalmitis open globe injury |
| title | Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| title_full | Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| title_fullStr | Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| title_full_unstemmed | Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| title_short | Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| title_sort | phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury |
| topic | sympathetic ophthalmia phacoanaphylactic endophthalmitis open globe injury |
| url | https://roj.igb.ru/jour/article/view/587 |
| work_keys_str_mv | AT nlleparskaya phacoanaphylacticendophthalmitisassympatheticophthalmiaaftercorneoscleralinjury AT ipkhoroshilovamaslova phacoanaphylacticendophthalmitisassympatheticophthalmiaaftercorneoscleralinjury AT asvoronin phacoanaphylacticendophthalmitisassympatheticophthalmiaaftercorneoscleralinjury |