Advances in Oncolytic Viral Therapy in Melanoma: A Comprehensive Review

QR Code

Advances in Oncolytic Viral Therapy in Melanoma: A Comprehensive Review

Checkpoint inhibitor therapy revolutionized the treatment of patients with melanoma. However, in patients where melanoma exhibits resistance to checkpoint inhibitor therapy, the treatment options are limited. Oncolytic viruses are a unique form of immunotherapy that uses live viruses to infect and l...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ayushi Garg, Rohit Rao, Felicia Tejawinata, Gazi Amena Noor Shamita, McKay S. Herpel, Akihiro Yoshida, Gordon Goolamier, Jessica Sidiropoulos, Iris Y. Sheng, Salim-Tamuz Abboud, Luke D. Rothermel, Nami Azar, Ankit Mangla
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Vaccines
Subjects:	oncolytic viruses melanoma immunotherapy history of oncolytic viruses T-VEC RP-1
Online Access:	https://www.mdpi.com/2076-393X/13/7/727
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Comparative safety and efficacy of oncolytic virotherapy for the treatment of individuals with malignancies: a systematic review, meta-analysis, and Bayesian network meta-analysisResearch in context
by: Poyee Lau, et al.
Published: (2025-08-01)

Modern Approaches to Enterovirus-Based Oncolytic Immune Virotherapy of Malignant Diseases
by: E. R. Nemtsova, et al.
Published: (2025-07-01)

Therapy gone viral: Exploring the use of oncolytic viruses in non-small cell lung cancer immunotherapy
by: Jemima Steele, et al.
Published: (2025-01-01)

Clinical trials on oncolytic viruses
by: I. V. Golovinov, et al.
Published: (2025-01-01)

The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors
by: F. E. Babaeva, et al.
Published: (2019-12-01)

Experimental models for developing oncolytic virotherapy for metastatic prostate cancer
by: Ying-Cheng Chen, et al.
Published: (2025-07-01)

Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG
by: M. A. Dymova, et al.
Published: (2024-01-01)

Oncolytic viruses in cancer therapy: Exploring the mechanisms and clinical potential of mammalian and avian reoviruses
by: Yi-Ying Wu, et al.
Published: (2025-01-01)

Oncolytic virus VG161 offers new hope for refractory liver cancer
by: Jinqiu Li, et al.
Published: (2025-07-01)

Advanced Therapy Medicines Based on Oncolytic Viruses (Part II: Development and Authorisation of IMLYGIC®)
by: E. V. Melnikova, et al.
Published: (2021-12-01)

A comparative study of replicative properties of antitumor recombinant vaccinia viruses on human glioblastoma cell culture U87 and monkey kidney cell culture CV-1
by: R. A. Maksyutov, et al.
Published: (2017-02-01)

A Type I IFN-Inducing Oncolytic Virus Improves NK Cell-Mediated Killing of Tumor Cells In Vitro Through Multiple Mechanisms
by: Elisabeth M. Shiffer, et al.
Published: (2025-06-01)

High Cell Density Perfusion Process of Quail Cells Producing Oncolytic rVSV‐NDV
by: Lennart Jacobtorweihe, et al.
Published: (2025-07-01)

Influence of oncolytic strains of a new unclassified group of human rotaviruses on peripheral blood lymphocytes
by: O. I. Kit, et al.
Published: (2021-09-01)

An attenuated coxsackievirus B5 mutant carrying VP1-N157K retains oncolytic potency against non-small cell lung cancer
by: Lifang Song, et al.
Published: (2025-09-01)

Evaluation of Apoptosis and Cytotoxicity Induction Using a Recombinant Newcastle Disease Virus Expressing Human IFN-γ in Human Prostate Cancer Cells In Vitro
by: Aldo Rojas-Neyra, et al.
Published: (2025-07-01)

Measles Virus as a Vector Platform for Glioblastoma Immunotherapy (Review)
by: E. Yu. Nikolaeva, et al.
Published: (2022-02-01)

Advanced Therapy Medicines Based on Oncolytic Viruses (Part I: Development and Authorisation of Products in China)
by: E. V. Melnikova, et al.
Published: (2021-10-01)

ONCOLYTIC VIROTHERAPY IN GLIOBLASTOMA TREATMENT: PROGRESS AND CHALLENGES IN CLINICAL RESEARCH (LITERATURE REVIEW)
by: O. I. Kit, et al.
Published: (2020-12-01)

Comparative analysis of oncolytic potential of vesicular stomatitis virus serotypes Indiana and New Jersey in cancer cell lines
by: A. S. Isaeva, et al.
Published: (2023-12-01)

A model of the artificial metastasis of human epidermoid carcinoma A431 in nude mice for examination of the oncolytic activity of vaccinia virus
by: G. V. Kochneva, et al.
Published: (2015-12-01)

Preclinical Safety Assessment of Antineoplastic Agents Based on Live Non-Pathogenic Enteroviruses
by: K. V. Sivak, et al.
Published: (2024-12-01)

Shaping viral immunotherapy towards cancer-targeted immunological cell death
by: Anastasia S. Isaeva, et al.
Published: (2025-07-01)

The dual promise of oncolytic viruses: selective targeting and therapeutic enhancement in cancer treatment
by: Alaa A. A. Aljabali, et al.
Published: (2025-07-01)

SELECTED ASPECTS OF ALLO- AND XENOGRAFT MODEL APPLICATIONS FOR DEVELOPING NOVEL ANTI-CANCER VACCINES AND ONCOLYTIC VIRUSES
by: T. S. Nepomnyashchikh, et al.
Published: (2019-05-01)

Antitumor effect of the Newcastle disease virus strain NDV/Altai/pigeon/777/2010 on a model of solid Lewis carcinoma
by: Yu. I. Karkavin, et al.
Published: (2024-10-01)

Oncolytic Adenovirus-Based Immunotherapy for Malignant Mesothelioma: Preclinical Advances and Future Perspectives
by: Garofalo Mariangela, et al.
Published: (2025-07-01)

Interventional oncology: A snapshot of expanding practice
by: Azzam Khankan
Published: (2017-01-01)

Interventional oncology: A snapshot of expanding practice
by: Azzam Khankan
Published: (2017-01-01)

Oncolytic herpes simplex virus reprograms cancer-associated fibroblasts to enhance antitumor immunity in pancreatic cancer
by: Feilong Zhou, et al.
Published: (2025-09-01)

Synergy of oncolytic adenovirus and immune checkpoint inhibitors: transforming cancer immunotherapy paradigms
by: Chong Cheng, et al.
Published: (2025-07-01)

SHORT OVERVIEW OF CLINICAL TRIALS WITH CURRENT IMMUNOTHERAPEUTIC TOOLS FOR CANCER TREATMENT
by: T. S. Nepomnyashchikh, et al.
Published: (2017-05-01)

Obtainingvaccinia virus with increased production of extracellular enveloped virions and directing GM-CSF synthesis as a promising basis for development of antitumor drug
by: T. V. Bauer, et al.
Published: (2020-04-01)

Intravesical VSVd51-GM-CSF virotherapy is superior to BCG in treating bladder cancer in preclinical and translational models
by: Lauren Daniel, et al.
Published: (2025-09-01)

OFFICIAL MEDICATIONS FOR ANTI-TUMOR GENE THERAPY
by: E. R. Nemtsova, et al.
Published: (2016-12-01)

Streptococcal effective molecules as promising antiсancer agents: <i>pros</i> and <i>cons</i>
by: Alexander N. Suvorov, et al.
Published: (2025-05-01)

Zika virus has an oncolytic activity against human glioblastoma U87 cells
by: V. A. Svyatchenko, et al.
Published: (2019-01-01)

HPLC DETERMINATION OF D-PANTHENOL AND GLYCYRRHETINIC ACID FROM A HERBAL ANTI-HERPETIC SUPPLEMENT
by: Elena Gabriela Oltean, et al.
Published: (2016-12-01)

Viruses : the smallest enemy /
by: Locke, David M. (David Millard), 1929-
Published: (1974)

Evaluation of possible approaches to the determination by the method rp hplc natural oils in repellent compositions
by: L. A. Nosikova, et al.
Published: (2015-10-01)